Chlorazepam structure

Chlorazepam

TL;DR: Chlorazepam (CAS 34985-87-0) is a chemical compound with molecular formula C18H16Cl4N2O3 and molecular weight 447.99 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

7-chloro-1-methyl-5-phenyl-3H-1,4-benzodiazepin-2-one;2,2,2-trichloroethane-1,1-diol

Also Known As: Chlorazepam, Clorazepat, Chloral hydrate-diazepam, CHLORAZEPAM [WHO-DD], EINECS 252-308-1

CAS: 34985-87-0
Molecular Formula C18H16Cl4N2O3
Molecular Weight 447.99 g/mol
LogP 3.8211
Topological Polar Surface Area 73.13 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 4
Rotatable Bonds 1
Exact Mass 447.99152
Heavy Atoms 27
Complexity 836.24554

Chemical Identifiers

CAS Number 34985-87-0
SMILES CN1C(=O)CN=C(C2=C1C=CC(=C2)Cl)C3=CC=CC=C3.C(C(Cl)(Cl)Cl)(O)O

Product Overview

Chlorazepam (CAS 34985-87-0), with molecular formula C18H16Cl4N2O3 and molecular weight 447.99 g/mol. IUPAC: 7-chloro-1-methyl-5-phenyl-3H-1,4-benzodiazepin-2-one;2,2,2-trichloroethane-1,1-diol.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Chlorazepam

XLogP
3.8211
TPSA (Topological Polar Surface Area)
73.13
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
4
Rotatable Bonds
1
Heavy Atoms
27
Complexity
836.24554
Exact Mass
447.99152
Monoisotopic Mass
449.98856
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Chlorazepam

The XLogP value of 3.8211 indicates that Chlorazepam is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 73.13 Ų falls within the moderate polarity range, balancing permeability and solubility for Chlorazepam. Following Lipinski's Rule of Five, Chlorazepam has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Chlorazepam?

The CAS number of Chlorazepam is 34985-87-0.

What is the molecular formula of Chlorazepam?

The molecular formula of Chlorazepam is C18H16Cl4N2O3.

What is the molecular weight of Chlorazepam?

The molecular weight of Chlorazepam is 447.99 g/mol.

Where can I buy Chlorazepam?

You can request a quote for Chlorazepam directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Chlorazepam?

Yes, KEHONG BIO provides custom synthesis services for Chlorazepam and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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