![(2E)-3-(2-chlorophenyl)-N-{5-[(4-nitrophenyl)sulfonyl]-1,3-thiazol-2-yl}prop-2-enamide structure](/static/products/3495/349538-47-2.webp)
(2E)-3-(2-chlorophenyl)-N-{5-[(4-nitrophenyl)sulfonyl]-1,3-thiazol-2-yl}prop-2-enamide
TL;DR: (2E)-3-(2-chlorophenyl)-N-{5-[(4-nitrophenyl)sulfonyl]-1,3-thiazol-2-yl}prop-2-enamide (CAS 349538-47-2) is a chemical compound with molecular formula C18H12ClN3O5S2 and molecular weight 448.99 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-3-(2-chlorophenyl)-N-[5-(4-nitrophenyl)sulfonyl-1,3-thiazol-2-yl]prop-2-enamide
Also Known As: (2E)-3-(2-chlorophenyl)-N-{5-[(4-nitrophenyl)sulfonyl]-1,3-thiazol-2-yl}prop-2-enamide, (E)-3-(2-chlorophenyl)-N-[5-(4-nitrophenyl)sulfonyl-1,3-thiazol-2-yl]prop-2-enamide, (E)-3-(2-chlorophenyl)-N-(5-((4-nitrophenyl)sulfonyl)thiazol-2-yl)acrylamide, (2E)-3-(2-CHLOROPHENYL)-N-[5-(4-NITROBENZENESULFONYL)-1,3-THIAZOL-2-YL]PROP-2-ENAMIDE, (2E)-3-(2-chlorophenyl)-N-{5-[(4-nitrophenyl)sulfonyl](1,3-thiazol-2-yl)}prop- 2-enamide
| Molecular Formula | C18H12ClN3O5S2 |
|---|---|
| Molecular Weight | 448.99 g/mol |
| LogP | 4.1894 |
| Topological Polar Surface Area | 119.27 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 6 |
| Exact Mass | 448.9907 |
| Heavy Atoms | 29 |
| Complexity | 1204.2444 |
Chemical Identifiers
| CAS Number | 349538-47-2 |
|---|---|
| SMILES | C1=CC=C(C(=C1)/C=C/C(=O)NC2=NC=C(S2)S(=O)(=O)C3=CC=C(C=C3)[N+](=O)[O-])Cl |
Product Overview
(2E)-3-(2-chlorophenyl)-N-{5-[(4-nitrophenyl)sulfonyl]-1,3-thiazol-2-yl}prop-2-enamide (CAS 349538-47-2), with molecular formula C18H12ClN3O5S2 and molecular weight 448.99 g/mol. IUPAC: (E)-3-(2-chlorophenyl)-N-[5-(4-nitrophenyl)sulfonyl-1,3-thiazol-2-yl]prop-2-enamide.
Chemical Property Profile of (2E)-3-(2-chlorophenyl)-N-{5-[(4-nitrophenyl)sulfonyl]-1,3-thiazol-2-yl}prop-2-enamide
Property Insights of (2E)-3-(2-chlorophenyl)-N-{5-[(4-nitrophenyl)sulfonyl]-1,3-thiazol-2-yl}prop-2-enamide
The XLogP value of 4.1894 indicates that (2E)-3-(2-chlorophenyl)-N-{5-[(4-nitrophenyl)sulfonyl]-1,3-thiazol-2-yl}prop-2-enamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 119.27 Ų falls within the moderate polarity range, balancing permeability and solubility for (2E)-3-(2-chlorophenyl)-N-{5-[(4-nitrophenyl)sulfonyl]-1,3-thiazol-2-yl}prop-2-enamide. Following Lipinski's Rule of Five, (2E)-3-(2-chlorophenyl)-N-{5-[(4-nitrophenyl)sulfonyl]-1,3-thiazol-2-yl}prop-2-enamide has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (2E)-3-(2-chlorophenyl)-N-{5-[(4-nitrophenyl)sulfonyl]-1,3-thiazol-2-yl}prop-2-enamide?
The CAS number of (2E)-3-(2-chlorophenyl)-N-{5-[(4-nitrophenyl)sulfonyl]-1,3-thiazol-2-yl}prop-2-enamide is 349538-47-2.
What is the molecular formula of (2E)-3-(2-chlorophenyl)-N-{5-[(4-nitrophenyl)sulfonyl]-1,3-thiazol-2-yl}prop-2-enamide?
The molecular formula of (2E)-3-(2-chlorophenyl)-N-{5-[(4-nitrophenyl)sulfonyl]-1,3-thiazol-2-yl}prop-2-enamide is C18H12ClN3O5S2.
What is the molecular weight of (2E)-3-(2-chlorophenyl)-N-{5-[(4-nitrophenyl)sulfonyl]-1,3-thiazol-2-yl}prop-2-enamide?
The molecular weight of (2E)-3-(2-chlorophenyl)-N-{5-[(4-nitrophenyl)sulfonyl]-1,3-thiazol-2-yl}prop-2-enamide is 448.99 g/mol.
Where can I buy (2E)-3-(2-chlorophenyl)-N-{5-[(4-nitrophenyl)sulfonyl]-1,3-thiazol-2-yl}prop-2-enamide?
You can request a quote for (2E)-3-(2-chlorophenyl)-N-{5-[(4-nitrophenyl)sulfonyl]-1,3-thiazol-2-yl}prop-2-enamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (2E)-3-(2-chlorophenyl)-N-{5-[(4-nitrophenyl)sulfonyl]-1,3-thiazol-2-yl}prop-2-enamide?
Yes, KEHONG BIO provides custom synthesis services for (2E)-3-(2-chlorophenyl)-N-{5-[(4-nitrophenyl)sulfonyl]-1,3-thiazol-2-yl}prop-2-enamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.