1-(5-Chloro-2-methoxybenzoyl)-4-(4-fluorophenyl)piperazine
TL;DR: 1-(5-Chloro-2-methoxybenzoyl)-4-(4-fluorophenyl)piperazine (CAS 349420-75-3) is a chemical compound with molecular formula C18H18ClFN2O2 and molecular weight 348.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(5-chloro-2-methoxyphenyl)-[4-(4-fluorophenyl)piperazin-1-yl]methanone
Also Known As: 1-(5-chloro-2-methoxybenzoyl)-4-(4-fluorophenyl)piperazine, (5-chloro-2-methoxyphenyl)[4-(4-fluorophenyl)piperazin-1-yl]methanone, (5-chloro-2-methoxyphenyl)-[4-(4-fluorophenyl)piperazin-1-yl]methanone, 5-chloro-2-methoxyphenyl 4-(4-fluorophenyl)piperazinyl ketone, (5-chloro-2-methoxyphenyl)(4-(4-fluorophenyl)piperazin-1-yl)methanone
| Molecular Formula | C18H18ClFN2O2 |
|---|---|
| Molecular Weight | 348.10 g/mol |
| LogP | 3.7 |
| Topological Polar Surface Area | 32.8 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 348.1041 |
| Heavy Atoms | 24 |
| Complexity | 423.0 |
Chemical Identifiers
| CAS Number | 349420-75-3 |
|---|---|
| SMILES | COC1=C(C=C(C=C1)Cl)C(=O)N2CCN(CC2)C3=CC=C(C=C3)F |
| InChIKey | HYVPZZCUGTVLKE-UHFFFAOYSA-N |
Product Overview
1-(5-Chloro-2-methoxybenzoyl)-4-(4-fluorophenyl)piperazine (CAS 349420-75-3), with molecular formula C18H18ClFN2O2 and molecular weight 348.10 g/mol. IUPAC: (5-chloro-2-methoxyphenyl)-[4-(4-fluorophenyl)piperazin-1-yl]methanone.
Chemical Property Profile of 1-(5-Chloro-2-methoxybenzoyl)-4-(4-fluorophenyl)piperazine
Property Insights of 1-(5-Chloro-2-methoxybenzoyl)-4-(4-fluorophenyl)piperazine
The XLogP value of 3.7 indicates that 1-(5-Chloro-2-methoxybenzoyl)-4-(4-fluorophenyl)piperazine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 32.8 Ų, 1-(5-Chloro-2-methoxybenzoyl)-4-(4-fluorophenyl)piperazine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-(5-Chloro-2-methoxybenzoyl)-4-(4-fluorophenyl)piperazine has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-(5-Chloro-2-methoxybenzoyl)-4-(4-fluorophenyl)piperazine?
The CAS number of 1-(5-Chloro-2-methoxybenzoyl)-4-(4-fluorophenyl)piperazine is 349420-75-3.
What is the molecular formula of 1-(5-Chloro-2-methoxybenzoyl)-4-(4-fluorophenyl)piperazine?
The molecular formula of 1-(5-Chloro-2-methoxybenzoyl)-4-(4-fluorophenyl)piperazine is C18H18ClFN2O2.
What is the molecular weight of 1-(5-Chloro-2-methoxybenzoyl)-4-(4-fluorophenyl)piperazine?
The molecular weight of 1-(5-Chloro-2-methoxybenzoyl)-4-(4-fluorophenyl)piperazine is 348.10 g/mol.
Where can I buy 1-(5-Chloro-2-methoxybenzoyl)-4-(4-fluorophenyl)piperazine?
You can request a quote for 1-(5-Chloro-2-methoxybenzoyl)-4-(4-fluorophenyl)piperazine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-(5-Chloro-2-methoxybenzoyl)-4-(4-fluorophenyl)piperazine?
Yes, KEHONG BIO provides custom synthesis services for 1-(5-Chloro-2-methoxybenzoyl)-4-(4-fluorophenyl)piperazine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.