2-(4-Chlorophenoxy)-5-(trifluoromethyl)aniline structure

2-(4-Chlorophenoxy)-5-(trifluoromethyl)aniline

TL;DR: 2-(4-Chlorophenoxy)-5-(trifluoromethyl)aniline (CAS 349-20-2) is a chemical compound with molecular formula C13H9ClF3NO and molecular weight 287.03 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

2-(4-chlorophenoxy)-5-(trifluoromethyl)aniline

Also Known As: 2-(4-Chlorophenoxy)-5-(trifluoromethyl)aniline, 2-Amino-4'-chloro-4-(trifluoromethyl) diphenylether, 2-Amino-4'-Chloro-4-Trifluoromethyl Diphenyl Ether, 2-AMINO-4-CHLORO-4-TRIFLUOROMETHYLDIPHENYLETHER, 2-AMINO-4'-CHLORO-4-TRIFLUOROMETHYL DIPHENYLETHER

CAS: 349-20-2
Molecular Formula C13H9ClF3NO
Molecular Weight 287.03 g/mol
LogP 3.9
Topological Polar Surface Area 35.3 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 5
Rotatable Bonds 2
Exact Mass 287.03247
Heavy Atoms 19
Complexity 292.0

Chemical Identifiers

CAS Number 349-20-2
SMILES C1=CC(=CC=C1OC2=C(C=C(C=C2)C(F)(F)F)N)Cl
InChIKey NOJRAHDRZWZNMV-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 3 IPC patent classification(s) across the SureChEMBL global patent database.

Heterocyclic Building Blocks (12 patents) Pharmaceutical Intermediates (95 patents) Polymer Intermediates (1 patents)

Product Overview

2-(4-Chlorophenoxy)-5-(trifluoromethyl)aniline (CAS 349-20-2), with molecular formula C13H9ClF3NO and molecular weight 287.03 g/mol. IUPAC: 2-(4-chlorophenoxy)-5-(trifluoromethyl)aniline.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 2-(4-Chlorophenoxy)-5-(trifluoromethyl)aniline

XLogP
3.9
TPSA (Topological Polar Surface Area)
35.3
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
5
Rotatable Bonds
2
Heavy Atoms
19
Complexity
292.0
Exact Mass
287.03247
Monoisotopic Mass
287.03247
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 2-(4-Chlorophenoxy)-5-(trifluoromethyl)aniline

The XLogP value of 3.9 indicates that 2-(4-Chlorophenoxy)-5-(trifluoromethyl)aniline is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 35.3 Ų, 2-(4-Chlorophenoxy)-5-(trifluoromethyl)aniline exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-(4-Chlorophenoxy)-5-(trifluoromethyl)aniline has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 2-(4-Chlorophenoxy)-5-(trifluoromethyl)aniline?

The CAS number of 2-(4-Chlorophenoxy)-5-(trifluoromethyl)aniline is 349-20-2.

What is the molecular formula of 2-(4-Chlorophenoxy)-5-(trifluoromethyl)aniline?

The molecular formula of 2-(4-Chlorophenoxy)-5-(trifluoromethyl)aniline is C13H9ClF3NO.

What is the molecular weight of 2-(4-Chlorophenoxy)-5-(trifluoromethyl)aniline?

The molecular weight of 2-(4-Chlorophenoxy)-5-(trifluoromethyl)aniline is 287.03 g/mol.

Where can I buy 2-(4-Chlorophenoxy)-5-(trifluoromethyl)aniline?

You can request a quote for 2-(4-Chlorophenoxy)-5-(trifluoromethyl)aniline directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 2-(4-Chlorophenoxy)-5-(trifluoromethyl)aniline?

Yes, KEHONG BIO provides custom synthesis services for 2-(4-Chlorophenoxy)-5-(trifluoromethyl)aniline and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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