AE-848/13196048
TL;DR: AE-848/13196048 (CAS 348151-40-6) is a chemical compound with molecular formula C25H21F4N5O and molecular weight 483.17 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[4-(4-fluorophenyl)piperazin-1-yl]-[5-(4-methylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone
Also Known As: AE-848/13196048, [4-(4-fluorophenyl)piperazin-1-yl]-[5-(4-methylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone, [4-(4-fluorophenyl)piperazin-1-yl][5-(4-methylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone, (4-(4-fluorophenyl)piperazin-1-yl)(5-(p-tolyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl)methanone, 2-{[4-(4-fluorophenyl)-1-piperazinyl]carbonyl}-5-(4-methylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
| Molecular Formula | C25H21F4N5O |
|---|---|
| Molecular Weight | 483.17 g/mol |
| LogP | 4.82502 |
| Topological Polar Surface Area | 53.74 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 483.1682 |
| Heavy Atoms | 35 |
| Complexity | 1372.2521 |
Chemical Identifiers
| CAS Number | 348151-40-6 |
|---|---|
| SMILES | CC1=CC=C(C=C1)C2=NC3=CC(=NN3C(=C2)C(F)(F)F)C(=O)N4CCN(CC4)C5=CC=C(C=C5)F |
Product Overview
AE-848/13196048 (CAS 348151-40-6), with molecular formula C25H21F4N5O and molecular weight 483.17 g/mol. IUPAC: [4-(4-fluorophenyl)piperazin-1-yl]-[5-(4-methylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone.
Chemical Property Profile of AE-848/13196048
Property Insights of AE-848/13196048
The XLogP value of 4.82502 indicates that AE-848/13196048 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 53.74 Ų, AE-848/13196048 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, AE-848/13196048 has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of AE-848/13196048?
The CAS number of AE-848/13196048 is 348151-40-6.
What is the molecular formula of AE-848/13196048?
The molecular formula of AE-848/13196048 is C25H21F4N5O.
What is the molecular weight of AE-848/13196048?
The molecular weight of AE-848/13196048 is 483.17 g/mol.
Where can I buy AE-848/13196048?
You can request a quote for AE-848/13196048 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for AE-848/13196048?
Yes, KEHONG BIO provides custom synthesis services for AE-848/13196048 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.