![n-[4-Chloro-3-(trifluoromethyl)phenyl]acetamide structure](/static/products/3489/348-90-3.webp)
n-[4-Chloro-3-(trifluoromethyl)phenyl]acetamide
TL;DR: n-[4-Chloro-3-(trifluoromethyl)phenyl]acetamide (CAS 348-90-3) is a chemical compound with molecular formula C9H7ClF3NO and molecular weight 237.02 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[4-chloro-3-(trifluoromethyl)phenyl]acetamide
Also Known As: Regorafenib Impurity J, n-[4-chloro-3-(trifluoromethyl)phenyl]acetamide, Regorafenib Impurity 10, N-(4-Chloro-3-(trifluoromethyl)phenyl)acetamide, Acetamide, N-(4-chloro-3-(trifluoromethyl)phenyl)-
| Molecular Formula | C9H7ClF3NO |
|---|---|
| Molecular Weight | 237.02 g/mol |
| LogP | 3.3 |
| Topological Polar Surface Area | 29.1 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 1 |
| Exact Mass | 237.01683 |
| Heavy Atoms | 15 |
| Complexity | 244.0 |
Chemical Identifiers
| CAS Number | 348-90-3 |
|---|---|
| SMILES | CC(=O)NC1=CC(=C(C=C1)Cl)C(F)(F)F |
| InChIKey | LWEJZUHNFUXTEC-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 3 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
n-[4-Chloro-3-(trifluoromethyl)phenyl]acetamide (CAS 348-90-3), with molecular formula C9H7ClF3NO and molecular weight 237.02 g/mol. IUPAC: N-[4-chloro-3-(trifluoromethyl)phenyl]acetamide.
Chemical Property Profile of n-[4-Chloro-3-(trifluoromethyl)phenyl]acetamide
Property Insights of n-[4-Chloro-3-(trifluoromethyl)phenyl]acetamide
The XLogP value of 3.3 indicates that n-[4-Chloro-3-(trifluoromethyl)phenyl]acetamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 29.1 Ų, n-[4-Chloro-3-(trifluoromethyl)phenyl]acetamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, n-[4-Chloro-3-(trifluoromethyl)phenyl]acetamide has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of n-[4-Chloro-3-(trifluoromethyl)phenyl]acetamide?
The CAS number of n-[4-Chloro-3-(trifluoromethyl)phenyl]acetamide is 348-90-3.
What is the molecular formula of n-[4-Chloro-3-(trifluoromethyl)phenyl]acetamide?
The molecular formula of n-[4-Chloro-3-(trifluoromethyl)phenyl]acetamide is C9H7ClF3NO.
What is the molecular weight of n-[4-Chloro-3-(trifluoromethyl)phenyl]acetamide?
The molecular weight of n-[4-Chloro-3-(trifluoromethyl)phenyl]acetamide is 237.02 g/mol.
Where can I buy n-[4-Chloro-3-(trifluoromethyl)phenyl]acetamide?
You can request a quote for n-[4-Chloro-3-(trifluoromethyl)phenyl]acetamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for n-[4-Chloro-3-(trifluoromethyl)phenyl]acetamide?
Yes, KEHONG BIO provides custom synthesis services for n-[4-Chloro-3-(trifluoromethyl)phenyl]acetamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.