![(5Z)-5-{(2E)-3-[4-(dimethylamino)phenyl]prop-2-en-1-ylidene}-1-(3-methylphenyl)pyrimidine-2,4,6(1H,3H,5H)-trione structure](/static/products/3473/347395-36-2.webp)
(5Z)-5-{(2E)-3-[4-(dimethylamino)phenyl]prop-2-en-1-ylidene}-1-(3-methylphenyl)pyrimidine-2,4,6(1H,3H,5H)-trione
TL;DR: (5Z)-5-{(2E)-3-[4-(dimethylamino)phenyl]prop-2-en-1-ylidene}-1-(3-methylphenyl)pyrimidine-2,4,6(1H,3H,5H)-trione (CAS 347395-36-2) is a chemical compound with molecular formula C22H21N3O3 and molecular weight 375.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(5Z)-5-[(E)-3-[4-(dimethylamino)phenyl]prop-2-enylidene]-1-(3-methylphenyl)-1,3-diazinane-2,4,6-trione
Also Known As: (5Z)-5-{(2E)-3-[4-(dimethylamino)phenyl]prop-2-en-1-ylidene}-1-(3-methylphenyl)pyrimidine-2,4,6(1H,3H,5H)-trione, (5Z)-5-[(E)-3-(4-dimethylaminophenyl)prop-2-enylidene]-1-(3-methylphenyl)-1,3-diazinane-2,4,6-trione, (5Z)-5-[(E)-3-[4-(dimethylamino)phenyl]prop-2-enylidene]-1-(3-methylphenyl)-1,3-diazinane-2,4,6-trione, (5Z)-5-{(2E)-3-[4-(dimethylamino)phenyl]prop-2-en-1-ylidene}-2-hydroxy-1-(3-methylphenyl)pyrimidine-4,6(1H,5H)-dione, (Z)-5-((E)-3-(4-(dimethylamino)phenyl)allylidene)-1-(m-tolyl)pyrimidine-2,4,6(1H,3H,5H)-trione
| Molecular Formula | C22H21N3O3 |
|---|---|
| Molecular Weight | 375.16 g/mol |
| LogP | 3.28362 |
| Topological Polar Surface Area | 69.72 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 4 |
| Exact Mass | 375.1583 |
| Heavy Atoms | 28 |
| Complexity | 988.3415 |
Chemical Identifiers
| CAS Number | 347395-36-2 |
|---|---|
| SMILES | CC1=CC(=CC=C1)N2C(=O)/C(=C\C=C\C3=CC=C(C=C3)N(C)C)/C(=O)NC2=O |
Product Overview
(5Z)-5-{(2E)-3-[4-(dimethylamino)phenyl]prop-2-en-1-ylidene}-1-(3-methylphenyl)pyrimidine-2,4,6(1H,3H,5H)-trione (CAS 347395-36-2), with molecular formula C22H21N3O3 and molecular weight 375.16 g/mol. IUPAC: (5Z)-5-[(E)-3-[4-(dimethylamino)phenyl]prop-2-enylidene]-1-(3-methylphenyl)-1,3-diazinane-2,4,6-trione.
Chemical Property Profile of (5Z)-5-{(2E)-3-[4-(dimethylamino)phenyl]prop-2-en-1-ylidene}-1-(3-methylphenyl)pyrimidine-2,4,6(1H,3H,5H)-trione
Property Insights of (5Z)-5-{(2E)-3-[4-(dimethylamino)phenyl]prop-2-en-1-ylidene}-1-(3-methylphenyl)pyrimidine-2,4,6(1H,3H,5H)-trione
The XLogP value of 3.28362 indicates that (5Z)-5-{(2E)-3-[4-(dimethylamino)phenyl]prop-2-en-1-ylidene}-1-(3-methylphenyl)pyrimidine-2,4,6(1H,3H,5H)-trione is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 69.72 Ų falls within the moderate polarity range, balancing permeability and solubility for (5Z)-5-{(2E)-3-[4-(dimethylamino)phenyl]prop-2-en-1-ylidene}-1-(3-methylphenyl)pyrimidine-2,4,6(1H,3H,5H)-trione. Following Lipinski's Rule of Five, (5Z)-5-{(2E)-3-[4-(dimethylamino)phenyl]prop-2-en-1-ylidene}-1-(3-methylphenyl)pyrimidine-2,4,6(1H,3H,5H)-trione has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (5Z)-5-{(2E)-3-[4-(dimethylamino)phenyl]prop-2-en-1-ylidene}-1-(3-methylphenyl)pyrimidine-2,4,6(1H,3H,5H)-trione?
The CAS number of (5Z)-5-{(2E)-3-[4-(dimethylamino)phenyl]prop-2-en-1-ylidene}-1-(3-methylphenyl)pyrimidine-2,4,6(1H,3H,5H)-trione is 347395-36-2.
What is the molecular formula of (5Z)-5-{(2E)-3-[4-(dimethylamino)phenyl]prop-2-en-1-ylidene}-1-(3-methylphenyl)pyrimidine-2,4,6(1H,3H,5H)-trione?
The molecular formula of (5Z)-5-{(2E)-3-[4-(dimethylamino)phenyl]prop-2-en-1-ylidene}-1-(3-methylphenyl)pyrimidine-2,4,6(1H,3H,5H)-trione is C22H21N3O3.
What is the molecular weight of (5Z)-5-{(2E)-3-[4-(dimethylamino)phenyl]prop-2-en-1-ylidene}-1-(3-methylphenyl)pyrimidine-2,4,6(1H,3H,5H)-trione?
The molecular weight of (5Z)-5-{(2E)-3-[4-(dimethylamino)phenyl]prop-2-en-1-ylidene}-1-(3-methylphenyl)pyrimidine-2,4,6(1H,3H,5H)-trione is 375.16 g/mol.
Where can I buy (5Z)-5-{(2E)-3-[4-(dimethylamino)phenyl]prop-2-en-1-ylidene}-1-(3-methylphenyl)pyrimidine-2,4,6(1H,3H,5H)-trione?
You can request a quote for (5Z)-5-{(2E)-3-[4-(dimethylamino)phenyl]prop-2-en-1-ylidene}-1-(3-methylphenyl)pyrimidine-2,4,6(1H,3H,5H)-trione directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (5Z)-5-{(2E)-3-[4-(dimethylamino)phenyl]prop-2-en-1-ylidene}-1-(3-methylphenyl)pyrimidine-2,4,6(1H,3H,5H)-trione?
Yes, KEHONG BIO provides custom synthesis services for (5Z)-5-{(2E)-3-[4-(dimethylamino)phenyl]prop-2-en-1-ylidene}-1-(3-methylphenyl)pyrimidine-2,4,6(1H,3H,5H)-trione and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.