(Z)-N-(2-(1H-indol-3-yl)ethyl)-2-cyano-3-(4-hydroxyphenyl)acrylamide
TL;DR: (Z)-N-(2-(1H-indol-3-yl)ethyl)-2-cyano-3-(4-hydroxyphenyl)acrylamide (CAS 347388-36-7) is a chemical compound with molecular formula C20H17N3O2 and molecular weight 331.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(Z)-2-cyano-3-(4-hydroxyphenyl)-N-[2-(1H-indol-3-yl)ethyl]prop-2-enamide
Also Known As: BAS 02895727, (Z)-N-(2-(1H-indol-3-yl)ethyl)-2-cyano-3-(4-hydroxyphenyl)acrylamide, 2-Cyano-3-(4-hydroxy-phenyl)-N-[2-(1H-indol-3-yl)-ethyl]-acrylamide, (Z)-2-cyano-3-(4-hydroxyphenyl)-N-[2-(1H-indol-3-yl)ethyl]prop-2-enamide
| Molecular Formula | C20H17N3O2 |
|---|---|
| Molecular Weight | 331.13 g/mol |
| LogP | 3.13938 |
| Topological Polar Surface Area | 88.91 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 5 |
| Exact Mass | 331.13208 |
| Heavy Atoms | 25 |
| Complexity | 962.52 |
Chemical Identifiers
| CAS Number | 347388-36-7 |
|---|---|
| SMILES | C1=CC=C2C(=C1)C(=CN2)CCNC(=O)/C(=C\C3=CC=C(C=C3)O)/C#N |
Product Overview
(Z)-N-(2-(1H-indol-3-yl)ethyl)-2-cyano-3-(4-hydroxyphenyl)acrylamide (CAS 347388-36-7), with molecular formula C20H17N3O2 and molecular weight 331.13 g/mol. IUPAC: (Z)-2-cyano-3-(4-hydroxyphenyl)-N-[2-(1H-indol-3-yl)ethyl]prop-2-enamide.
Chemical Property Profile of (Z)-N-(2-(1H-indol-3-yl)ethyl)-2-cyano-3-(4-hydroxyphenyl)acrylamide
Property Insights of (Z)-N-(2-(1H-indol-3-yl)ethyl)-2-cyano-3-(4-hydroxyphenyl)acrylamide
The XLogP value of 3.13938 indicates that (Z)-N-(2-(1H-indol-3-yl)ethyl)-2-cyano-3-(4-hydroxyphenyl)acrylamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 88.91 Ų falls within the moderate polarity range, balancing permeability and solubility for (Z)-N-(2-(1H-indol-3-yl)ethyl)-2-cyano-3-(4-hydroxyphenyl)acrylamide. Following Lipinski's Rule of Five, (Z)-N-(2-(1H-indol-3-yl)ethyl)-2-cyano-3-(4-hydroxyphenyl)acrylamide has 3 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (Z)-N-(2-(1H-indol-3-yl)ethyl)-2-cyano-3-(4-hydroxyphenyl)acrylamide?
The CAS number of (Z)-N-(2-(1H-indol-3-yl)ethyl)-2-cyano-3-(4-hydroxyphenyl)acrylamide is 347388-36-7.
What is the molecular formula of (Z)-N-(2-(1H-indol-3-yl)ethyl)-2-cyano-3-(4-hydroxyphenyl)acrylamide?
The molecular formula of (Z)-N-(2-(1H-indol-3-yl)ethyl)-2-cyano-3-(4-hydroxyphenyl)acrylamide is C20H17N3O2.
What is the molecular weight of (Z)-N-(2-(1H-indol-3-yl)ethyl)-2-cyano-3-(4-hydroxyphenyl)acrylamide?
The molecular weight of (Z)-N-(2-(1H-indol-3-yl)ethyl)-2-cyano-3-(4-hydroxyphenyl)acrylamide is 331.13 g/mol.
Where can I buy (Z)-N-(2-(1H-indol-3-yl)ethyl)-2-cyano-3-(4-hydroxyphenyl)acrylamide?
You can request a quote for (Z)-N-(2-(1H-indol-3-yl)ethyl)-2-cyano-3-(4-hydroxyphenyl)acrylamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (Z)-N-(2-(1H-indol-3-yl)ethyl)-2-cyano-3-(4-hydroxyphenyl)acrylamide?
Yes, KEHONG BIO provides custom synthesis services for (Z)-N-(2-(1H-indol-3-yl)ethyl)-2-cyano-3-(4-hydroxyphenyl)acrylamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.