2-(2-chlorophenyl)-N-(4-ethoxyphenyl)quinazolin-4-amine
TL;DR: 2-(2-chlorophenyl)-N-(4-ethoxyphenyl)quinazolin-4-amine (CAS 347366-42-1) is a chemical compound with molecular formula C22H18ClN3O and molecular weight 375.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-(2-chlorophenyl)-N-(4-ethoxyphenyl)quinazolin-4-amine
Also Known As: 2-(2-chlorophenyl)-N-(4-ethoxyphenyl)quinazolin-4-amine, [2-(2-chlorophenyl)quinazolin-4-yl](4-ethoxyphenyl)amine, N-[(4Z)-2-(2-chlorophenyl)quinazolin-4(3H)-ylidene]-4-ethoxyaniline
| Molecular Formula | C22H18ClN3O |
|---|---|
| Molecular Weight | 375.11 g/mol |
| LogP | 6.0925 |
| Topological Polar Surface Area | 47.04 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 5 |
| Exact Mass | 375.11383 |
| Heavy Atoms | 27 |
| Complexity | 1080.3401 |
Chemical Identifiers
| CAS Number | 347366-42-1 |
|---|---|
| SMILES | CCOC1=CC=C(C=C1)NC2=NC(=NC3=CC=CC=C32)C4=CC=CC=C4Cl |
Product Overview
2-(2-chlorophenyl)-N-(4-ethoxyphenyl)quinazolin-4-amine (CAS 347366-42-1), with molecular formula C22H18ClN3O and molecular weight 375.11 g/mol. IUPAC: 2-(2-chlorophenyl)-N-(4-ethoxyphenyl)quinazolin-4-amine.
Chemical Property Profile of 2-(2-chlorophenyl)-N-(4-ethoxyphenyl)quinazolin-4-amine
Property Insights of 2-(2-chlorophenyl)-N-(4-ethoxyphenyl)quinazolin-4-amine
The XLogP value of 6.0925 indicates that 2-(2-chlorophenyl)-N-(4-ethoxyphenyl)quinazolin-4-amine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 47.04 Ų, 2-(2-chlorophenyl)-N-(4-ethoxyphenyl)quinazolin-4-amine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-(2-chlorophenyl)-N-(4-ethoxyphenyl)quinazolin-4-amine has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-(2-chlorophenyl)-N-(4-ethoxyphenyl)quinazolin-4-amine?
The CAS number of 2-(2-chlorophenyl)-N-(4-ethoxyphenyl)quinazolin-4-amine is 347366-42-1.
What is the molecular formula of 2-(2-chlorophenyl)-N-(4-ethoxyphenyl)quinazolin-4-amine?
The molecular formula of 2-(2-chlorophenyl)-N-(4-ethoxyphenyl)quinazolin-4-amine is C22H18ClN3O.
What is the molecular weight of 2-(2-chlorophenyl)-N-(4-ethoxyphenyl)quinazolin-4-amine?
The molecular weight of 2-(2-chlorophenyl)-N-(4-ethoxyphenyl)quinazolin-4-amine is 375.11 g/mol.
Where can I buy 2-(2-chlorophenyl)-N-(4-ethoxyphenyl)quinazolin-4-amine?
You can request a quote for 2-(2-chlorophenyl)-N-(4-ethoxyphenyl)quinazolin-4-amine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-(2-chlorophenyl)-N-(4-ethoxyphenyl)quinazolin-4-amine?
Yes, KEHONG BIO provides custom synthesis services for 2-(2-chlorophenyl)-N-(4-ethoxyphenyl)quinazolin-4-amine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.