4-Isoxazolecarbonyl chloride, 5-(2-chloro-6-fluorophenyl)-3-methyl- structure

4-Isoxazolecarbonyl chloride, 5-(2-chloro-6-fluorophenyl)-3-methyl-

TL;DR: 4-Isoxazolecarbonyl chloride, 5-(2-chloro-6-fluorophenyl)-3-methyl- (CAS 347186-83-8) is a chemical compound with molecular formula C11H6Cl2FNO2 and molecular weight 272.98 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

5-(2-chloro-6-fluorophenyl)-3-methyl-1,2-oxazole-4-carbonyl chloride

Also Known As: 3-(1,1-Dimethyl-3-oxobutyl)-5-phenylisoxazol, 4-Isoxazolecarbonyl chloride, 5-(2-chloro-6-fluorophenyl)-3-methyl-, 5-(2-chloro-6-fluorophenyl)-3-methylisoxazole-4-carbonyl chloride, 5-(2-CHLORO-6-FLUOROPHENYL)-3-METHYL-1,2-OXAZOLE-4-CARBONYL CHLORIDE, 5-(2-chloro-6-fluoro-phenyl)-3-methyl-1,2-oxazole-4-carbonyl Chloride

CAS: 347186-83-8
Molecular Formula C11H6Cl2FNO2
Molecular Weight 272.98 g/mol
LogP 3.82152
Topological Polar Surface Area 43.1 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 3
Rotatable Bonds 2
Exact Mass 272.97595
Heavy Atoms 17
Complexity 574.9025

Chemical Identifiers

CAS Number 347186-83-8
SMILES CC1=NOC(=C1C(=O)Cl)C2=C(C=CC=C2Cl)F

Product Overview

4-Isoxazolecarbonyl chloride, 5-(2-chloro-6-fluorophenyl)-3-methyl- (CAS 347186-83-8), with molecular formula C11H6Cl2FNO2 and molecular weight 272.98 g/mol. IUPAC: 5-(2-chloro-6-fluorophenyl)-3-methyl-1,2-oxazole-4-carbonyl chloride.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 4-Isoxazolecarbonyl chloride, 5-(2-chloro-6-fluorophenyl)-3-methyl-

XLogP
3.82152
TPSA (Topological Polar Surface Area)
43.1
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
3
Rotatable Bonds
2
Heavy Atoms
17
Complexity
574.9025
Exact Mass
272.97595
Monoisotopic Mass
272.97595
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 4-Isoxazolecarbonyl chloride, 5-(2-chloro-6-fluorophenyl)-3-methyl-

The XLogP value of 3.82152 indicates that 4-Isoxazolecarbonyl chloride, 5-(2-chloro-6-fluorophenyl)-3-methyl- is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 43.1 Ų, 4-Isoxazolecarbonyl chloride, 5-(2-chloro-6-fluorophenyl)-3-methyl- exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-Isoxazolecarbonyl chloride, 5-(2-chloro-6-fluorophenyl)-3-methyl- has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 4-Isoxazolecarbonyl chloride, 5-(2-chloro-6-fluorophenyl)-3-methyl-?

The CAS number of 4-Isoxazolecarbonyl chloride, 5-(2-chloro-6-fluorophenyl)-3-methyl- is 347186-83-8.

What is the molecular formula of 4-Isoxazolecarbonyl chloride, 5-(2-chloro-6-fluorophenyl)-3-methyl-?

The molecular formula of 4-Isoxazolecarbonyl chloride, 5-(2-chloro-6-fluorophenyl)-3-methyl- is C11H6Cl2FNO2.

What is the molecular weight of 4-Isoxazolecarbonyl chloride, 5-(2-chloro-6-fluorophenyl)-3-methyl-?

The molecular weight of 4-Isoxazolecarbonyl chloride, 5-(2-chloro-6-fluorophenyl)-3-methyl- is 272.98 g/mol.

Where can I buy 4-Isoxazolecarbonyl chloride, 5-(2-chloro-6-fluorophenyl)-3-methyl-?

You can request a quote for 4-Isoxazolecarbonyl chloride, 5-(2-chloro-6-fluorophenyl)-3-methyl- directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 4-Isoxazolecarbonyl chloride, 5-(2-chloro-6-fluorophenyl)-3-methyl-?

Yes, KEHONG BIO provides custom synthesis services for 4-Isoxazolecarbonyl chloride, 5-(2-chloro-6-fluorophenyl)-3-methyl- and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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