5-(Chloromethyl)-4-(4-fluorophenyl)-2-methyl-1,3-thiazole
TL;DR: 5-(Chloromethyl)-4-(4-fluorophenyl)-2-methyl-1,3-thiazole (CAS 347174-12-3) is a chemical compound with molecular formula C11H9ClFNS and molecular weight 241.01 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-(chloromethyl)-4-(4-fluorophenyl)-2-methyl-1,3-thiazole
Also Known As: 4-(4-fluorophenyl)-5-chloromethyl-2-methylthiazole, 5-(chloromethyl)-4-(4-fluorophenyl)-2-methyl-1,3-thiazole
| Molecular Formula | C11H9ClFNS |
|---|---|
| Molecular Weight | 241.01 g/mol |
| LogP | 3.99642 |
| Topological Polar Surface Area | 12.89 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 2 |
| Exact Mass | 241.01283 |
| Heavy Atoms | 15 |
| Complexity | 463.94022 |
Chemical Identifiers
| CAS Number | 347174-12-3 |
|---|---|
| SMILES | CC1=NC(=C(S1)CCl)C2=CC=C(C=C2)F |
Product Overview
5-(Chloromethyl)-4-(4-fluorophenyl)-2-methyl-1,3-thiazole (CAS 347174-12-3), with molecular formula C11H9ClFNS and molecular weight 241.01 g/mol. IUPAC: 5-(chloromethyl)-4-(4-fluorophenyl)-2-methyl-1,3-thiazole.
Chemical Property Profile of 5-(Chloromethyl)-4-(4-fluorophenyl)-2-methyl-1,3-thiazole
Property Insights of 5-(Chloromethyl)-4-(4-fluorophenyl)-2-methyl-1,3-thiazole
The XLogP value of 3.99642 indicates that 5-(Chloromethyl)-4-(4-fluorophenyl)-2-methyl-1,3-thiazole is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 12.89 Ų, 5-(Chloromethyl)-4-(4-fluorophenyl)-2-methyl-1,3-thiazole exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 5-(Chloromethyl)-4-(4-fluorophenyl)-2-methyl-1,3-thiazole has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5-(Chloromethyl)-4-(4-fluorophenyl)-2-methyl-1,3-thiazole?
The CAS number of 5-(Chloromethyl)-4-(4-fluorophenyl)-2-methyl-1,3-thiazole is 347174-12-3.
What is the molecular formula of 5-(Chloromethyl)-4-(4-fluorophenyl)-2-methyl-1,3-thiazole?
The molecular formula of 5-(Chloromethyl)-4-(4-fluorophenyl)-2-methyl-1,3-thiazole is C11H9ClFNS.
What is the molecular weight of 5-(Chloromethyl)-4-(4-fluorophenyl)-2-methyl-1,3-thiazole?
The molecular weight of 5-(Chloromethyl)-4-(4-fluorophenyl)-2-methyl-1,3-thiazole is 241.01 g/mol.
Where can I buy 5-(Chloromethyl)-4-(4-fluorophenyl)-2-methyl-1,3-thiazole?
You can request a quote for 5-(Chloromethyl)-4-(4-fluorophenyl)-2-methyl-1,3-thiazole directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5-(Chloromethyl)-4-(4-fluorophenyl)-2-methyl-1,3-thiazole?
Yes, KEHONG BIO provides custom synthesis services for 5-(Chloromethyl)-4-(4-fluorophenyl)-2-methyl-1,3-thiazole and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.