![1-[2-Chloro-5-(trifluoromethyl)phenyl]piperazine structure](/static/products/3467/346729-49-5.webp)
1-[2-Chloro-5-(trifluoromethyl)phenyl]piperazine
TL;DR: 1-[2-Chloro-5-(trifluoromethyl)phenyl]piperazine (CAS 346729-49-5) is a chemical compound with molecular formula C11H12ClF3N2 and molecular weight 264.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[2-chloro-5-(trifluoromethyl)phenyl]piperazine
Also Known As: 1-[2-chloro-5-(trifluoromethyl)phenyl]piperazine, 1-(2-chloro-5-(trifluoromethyl)phenyl)piperazine, 1-(2-Chloro-5-trifluoromethyl-phenyl)-piperazine
| Molecular Formula | C11H12ClF3N2 |
|---|---|
| Molecular Weight | 264.06 g/mol |
| LogP | 2.7684 |
| Topological Polar Surface Area | 15.27 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 1 |
| Exact Mass | 264.06412 |
| Heavy Atoms | 17 |
| Complexity | 400.1933 |
Chemical Identifiers
| CAS Number | 346729-49-5 |
|---|---|
| SMILES | C1CN(CCN1)C2=C(C=CC(=C2)C(F)(F)F)Cl |
Product Overview
1-[2-Chloro-5-(trifluoromethyl)phenyl]piperazine (CAS 346729-49-5), with molecular formula C11H12ClF3N2 and molecular weight 264.06 g/mol. IUPAC: 1-[2-chloro-5-(trifluoromethyl)phenyl]piperazine.
Chemical Property Profile of 1-[2-Chloro-5-(trifluoromethyl)phenyl]piperazine
Property Insights of 1-[2-Chloro-5-(trifluoromethyl)phenyl]piperazine
The XLogP value of 2.7684 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 1-[2-Chloro-5-(trifluoromethyl)phenyl]piperazine. With a topological polar surface area (TPSA) of 15.27 Ų, 1-[2-Chloro-5-(trifluoromethyl)phenyl]piperazine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-[2-Chloro-5-(trifluoromethyl)phenyl]piperazine has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-[2-Chloro-5-(trifluoromethyl)phenyl]piperazine?
The CAS number of 1-[2-Chloro-5-(trifluoromethyl)phenyl]piperazine is 346729-49-5.
What is the molecular formula of 1-[2-Chloro-5-(trifluoromethyl)phenyl]piperazine?
The molecular formula of 1-[2-Chloro-5-(trifluoromethyl)phenyl]piperazine is C11H12ClF3N2.
What is the molecular weight of 1-[2-Chloro-5-(trifluoromethyl)phenyl]piperazine?
The molecular weight of 1-[2-Chloro-5-(trifluoromethyl)phenyl]piperazine is 264.06 g/mol.
Where can I buy 1-[2-Chloro-5-(trifluoromethyl)phenyl]piperazine?
You can request a quote for 1-[2-Chloro-5-(trifluoromethyl)phenyl]piperazine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-[2-Chloro-5-(trifluoromethyl)phenyl]piperazine?
Yes, KEHONG BIO provides custom synthesis services for 1-[2-Chloro-5-(trifluoromethyl)phenyl]piperazine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.