A2488/0105778
TL;DR: A2488/0105778 (CAS 346716-62-9) is a chemical compound with molecular formula C20H17F2NO4S and molecular weight 405.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
dimethyl 4-(2,5-difluorophenyl)-1-(thiophen-2-ylmethyl)-4H-pyridine-3,5-dicarboxylate
Also Known As: A2488/0105778, dimethyl 4-(2,5-difluorophenyl)-1-(thiophen-2-ylmethyl)-1,4-dihydropyridine-3,5-dicarboxylate, dimethyl 4-(2,5-difluorophenyl)-1-(thiophen-2-ylmethyl)-4H-pyridine-3,5-dicarboxylate, DIMETHYL 4-(2,5-DIFLUOROPHENYL)-1-(2-THIENYLMETHYL)-1,4-DIHYDRO-3,5-PYRIDINEDICARBOXYLATE, methyl 4-(2,5-difluorophenyl)-5-(methoxycarbonyl)-1-(2-thienylmethyl)-1,4-dihy dropyridine-3-carboxylate
| Molecular Formula | C20H17F2NO4S |
|---|---|
| Molecular Weight | 405.08 g/mol |
| LogP | 3.7395 |
| Topological Polar Surface Area | 55.84 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 5 |
| Exact Mass | 405.08463 |
| Heavy Atoms | 28 |
| Complexity | 919.12024 |
Chemical Identifiers
| CAS Number | 346716-62-9 |
|---|---|
| SMILES | COC(=O)C1=CN(C=C(C1C2=C(C=CC(=C2)F)F)C(=O)OC)CC3=CC=CS3 |
Product Overview
A2488/0105778 (CAS 346716-62-9), with molecular formula C20H17F2NO4S and molecular weight 405.08 g/mol. IUPAC: dimethyl 4-(2,5-difluorophenyl)-1-(thiophen-2-ylmethyl)-4H-pyridine-3,5-dicarboxylate.
Chemical Property Profile of A2488/0105778
Property Insights of A2488/0105778
The XLogP value of 3.7395 indicates that A2488/0105778 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 55.84 Ų, A2488/0105778 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, A2488/0105778 has 0 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of A2488/0105778?
The CAS number of A2488/0105778 is 346716-62-9.
What is the molecular formula of A2488/0105778?
The molecular formula of A2488/0105778 is C20H17F2NO4S.
What is the molecular weight of A2488/0105778?
The molecular weight of A2488/0105778 is 405.08 g/mol.
Where can I buy A2488/0105778?
You can request a quote for A2488/0105778 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for A2488/0105778?
Yes, KEHONG BIO provides custom synthesis services for A2488/0105778 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.