A3353/0142301
TL;DR: A3353/0142301 (CAS 346445-04-3) is a chemical compound with molecular formula C20H18N4OS and molecular weight 362.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(6E)-6-[[4-(dimethylamino)phenyl]methylidene]-3-(4-methylphenyl)-[1,3]thiazolo[2,3-c][1,2,4]triazol-5-one
Also Known As: A3353/0142301, (E)-6-(4-(dimethylamino)benzylidene)-3-(p-tolyl)thiazolo[2,3-c][1,2,4]triazol-5(6H)-one, (6E)-6-[(4-dimethylaminophenyl)methylidene]-3-(4-methylphenyl)-[1,3]thiazolo[2,3-c][1,2,4]triazol-5-one, (6E)-6-{[4-(DIMETHYLAMINO)PHENYL]METHYLIDENE}-3-(4-METHYLPHENYL)-5H,6H-[1,2,4]TRIAZOLO[3,4-B][1,3]THIAZOL-5-ONE
| Molecular Formula | C20H18N4OS |
|---|---|
| Molecular Weight | 362.12 g/mol |
| LogP | 2.74012 |
| Topological Polar Surface Area | 50.5 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 3 |
| Exact Mass | 362.12012 |
| Heavy Atoms | 26 |
| Complexity | 1171.7524 |
Chemical Identifiers
| CAS Number | 346445-04-3 |
|---|---|
| SMILES | CC1=CC=C(C=C1)C2=NN=C3N2C(=O)/C(=C\C4=CC=C(C=C4)N(C)C)/S3 |
Product Overview
A3353/0142301 (CAS 346445-04-3), with molecular formula C20H18N4OS and molecular weight 362.12 g/mol. IUPAC: (6E)-6-[[4-(dimethylamino)phenyl]methylidene]-3-(4-methylphenyl)-[1,3]thiazolo[2,3-c][1,2,4]triazol-5-one.
Chemical Property Profile of A3353/0142301
Property Insights of A3353/0142301
The XLogP value of 2.74012 suggests moderate lipophilicity, balancing water solubility and membrane permeability for A3353/0142301. With a topological polar surface area (TPSA) of 50.5 Ų, A3353/0142301 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, A3353/0142301 has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of A3353/0142301?
The CAS number of A3353/0142301 is 346445-04-3.
What is the molecular formula of A3353/0142301?
The molecular formula of A3353/0142301 is C20H18N4OS.
What is the molecular weight of A3353/0142301?
The molecular weight of A3353/0142301 is 362.12 g/mol.
Where can I buy A3353/0142301?
You can request a quote for A3353/0142301 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for A3353/0142301?
Yes, KEHONG BIO provides custom synthesis services for A3353/0142301 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.