alpha,alpha,alpha-Trifluoro-3-nitro-4-(phenylthio)toluene structure

alpha,alpha,alpha-Trifluoro-3-nitro-4-(phenylthio)toluene

TL;DR: alpha,alpha,alpha-Trifluoro-3-nitro-4-(phenylthio)toluene (CAS 346-44-1) is a chemical compound with molecular formula C13H8F3NO2S and molecular weight 299.02 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

2-nitro-1-phenylsulfanyl-4-(trifluoromethyl)benzene

Also Known As: 2-Nitro-4-(trifluoromethyl)phenyl phenyl sulfide, 2-nitro-1-(phenylsulfanyl)-4-(trifluoromethyl)benzene, alpha,alpha,alpha-Trifluoro-3-nitro-4-(phenylthio)toluene, 2-nitro-1-phenylsulfanyl-4-(trifluoromethyl)benzene, (2-nitro-4-(trifluoromethyl)phenyl)(phenyl)sulfane

CAS: 346-44-1
Molecular Formula C13H8F3NO2S
Molecular Weight 299.02 g/mol
LogP 4.2
Topological Polar Surface Area 71.1 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 6
Rotatable Bonds 2
Exact Mass 299.0228
Heavy Atoms 20
Complexity 339.0

Chemical Identifiers

CAS Number 346-44-1
SMILES C1=CC=C(C=C1)SC2=C(C=C(C=C2)C(F)(F)F)[N+](=O)[O-]
InChIKey UBCNQWMQLBEUOC-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 1 IPC patent classification(s) across the SureChEMBL global patent database.

Heterocyclic Building Blocks (2 patents)

Product Overview

alpha,alpha,alpha-Trifluoro-3-nitro-4-(phenylthio)toluene (CAS 346-44-1), with molecular formula C13H8F3NO2S and molecular weight 299.02 g/mol. IUPAC: 2-nitro-1-phenylsulfanyl-4-(trifluoromethyl)benzene.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of alpha,alpha,alpha-Trifluoro-3-nitro-4-(phenylthio)toluene

XLogP
4.2
TPSA (Topological Polar Surface Area)
71.1
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
6
Rotatable Bonds
2
Heavy Atoms
20
Complexity
339.0
Exact Mass
299.0228
Monoisotopic Mass
299.0228
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of alpha,alpha,alpha-Trifluoro-3-nitro-4-(phenylthio)toluene

The XLogP value of 4.2 indicates that alpha,alpha,alpha-Trifluoro-3-nitro-4-(phenylthio)toluene is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 71.1 Ų falls within the moderate polarity range, balancing permeability and solubility for alpha,alpha,alpha-Trifluoro-3-nitro-4-(phenylthio)toluene. Following Lipinski's Rule of Five, alpha,alpha,alpha-Trifluoro-3-nitro-4-(phenylthio)toluene has 0 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of alpha,alpha,alpha-Trifluoro-3-nitro-4-(phenylthio)toluene?

The CAS number of alpha,alpha,alpha-Trifluoro-3-nitro-4-(phenylthio)toluene is 346-44-1.

What is the molecular formula of alpha,alpha,alpha-Trifluoro-3-nitro-4-(phenylthio)toluene?

The molecular formula of alpha,alpha,alpha-Trifluoro-3-nitro-4-(phenylthio)toluene is C13H8F3NO2S.

What is the molecular weight of alpha,alpha,alpha-Trifluoro-3-nitro-4-(phenylthio)toluene?

The molecular weight of alpha,alpha,alpha-Trifluoro-3-nitro-4-(phenylthio)toluene is 299.02 g/mol.

Where can I buy alpha,alpha,alpha-Trifluoro-3-nitro-4-(phenylthio)toluene?

You can request a quote for alpha,alpha,alpha-Trifluoro-3-nitro-4-(phenylthio)toluene directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for alpha,alpha,alpha-Trifluoro-3-nitro-4-(phenylthio)toluene?

Yes, KEHONG BIO provides custom synthesis services for alpha,alpha,alpha-Trifluoro-3-nitro-4-(phenylthio)toluene and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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