![1-(2-fluorobenzyl)-1'H-spiro[indole-3,2'-quinazoline]-2,4'(1H,3'H)-dione structure](/static/products/3459/345991-82-4.webp)
1-(2-fluorobenzyl)-1'H-spiro[indole-3,2'-quinazoline]-2,4'(1H,3'H)-dione
TL;DR: 1-(2-fluorobenzyl)-1'H-spiro[indole-3,2'-quinazoline]-2,4'(1H,3'H)-dione (CAS 345991-82-4) is a chemical compound with molecular formula C22H16FN3O2 and molecular weight 373.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1'-[(2-fluorophenyl)methyl]spiro[1,3-dihydroquinazoline-2,3'-indole]-2',4-dione
Also Known As: 1-(2-fluorobenzyl)-1'H-spiro[indole-3,2'-quinazoline]-2,4'(1H,3'H)-dione, A2523/0107230, 1'-[(2-fluorophenyl)methyl]spiro[1,3-dihydroquinazoline-2,3'-indole]-2',4-dione, 11-[(2-fluorophenyl)methyl]spiro[1,2,3-trihydroquinazoline-2,3'-indoline]-4,12 -dione
| Molecular Formula | C22H16FN3O2 |
|---|---|
| Molecular Weight | 373.12 g/mol |
| LogP | 3.3808 |
| Topological Polar Surface Area | 61.44 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 373.12265 |
| Heavy Atoms | 28 |
| Complexity | 1130.0245 |
Chemical Identifiers
| CAS Number | 345991-82-4 |
|---|---|
| SMILES | C1=CC=C(C(=C1)CN2C3=CC=CC=C3C4(C2=O)NC5=CC=CC=C5C(=O)N4)F |
Product Overview
1-(2-fluorobenzyl)-1'H-spiro[indole-3,2'-quinazoline]-2,4'(1H,3'H)-dione (CAS 345991-82-4), with molecular formula C22H16FN3O2 and molecular weight 373.12 g/mol. IUPAC: 1'-[(2-fluorophenyl)methyl]spiro[1,3-dihydroquinazoline-2,3'-indole]-2',4-dione.
Chemical Property Profile of 1-(2-fluorobenzyl)-1'H-spiro[indole-3,2'-quinazoline]-2,4'(1H,3'H)-dione
Property Insights of 1-(2-fluorobenzyl)-1'H-spiro[indole-3,2'-quinazoline]-2,4'(1H,3'H)-dione
The XLogP value of 3.3808 indicates that 1-(2-fluorobenzyl)-1'H-spiro[indole-3,2'-quinazoline]-2,4'(1H,3'H)-dione is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 61.44 Ų falls within the moderate polarity range, balancing permeability and solubility for 1-(2-fluorobenzyl)-1'H-spiro[indole-3,2'-quinazoline]-2,4'(1H,3'H)-dione. Following Lipinski's Rule of Five, 1-(2-fluorobenzyl)-1'H-spiro[indole-3,2'-quinazoline]-2,4'(1H,3'H)-dione has 2 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-(2-fluorobenzyl)-1'H-spiro[indole-3,2'-quinazoline]-2,4'(1H,3'H)-dione?
The CAS number of 1-(2-fluorobenzyl)-1'H-spiro[indole-3,2'-quinazoline]-2,4'(1H,3'H)-dione is 345991-82-4.
What is the molecular formula of 1-(2-fluorobenzyl)-1'H-spiro[indole-3,2'-quinazoline]-2,4'(1H,3'H)-dione?
The molecular formula of 1-(2-fluorobenzyl)-1'H-spiro[indole-3,2'-quinazoline]-2,4'(1H,3'H)-dione is C22H16FN3O2.
What is the molecular weight of 1-(2-fluorobenzyl)-1'H-spiro[indole-3,2'-quinazoline]-2,4'(1H,3'H)-dione?
The molecular weight of 1-(2-fluorobenzyl)-1'H-spiro[indole-3,2'-quinazoline]-2,4'(1H,3'H)-dione is 373.12 g/mol.
Where can I buy 1-(2-fluorobenzyl)-1'H-spiro[indole-3,2'-quinazoline]-2,4'(1H,3'H)-dione?
You can request a quote for 1-(2-fluorobenzyl)-1'H-spiro[indole-3,2'-quinazoline]-2,4'(1H,3'H)-dione directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-(2-fluorobenzyl)-1'H-spiro[indole-3,2'-quinazoline]-2,4'(1H,3'H)-dione?
Yes, KEHONG BIO provides custom synthesis services for 1-(2-fluorobenzyl)-1'H-spiro[indole-3,2'-quinazoline]-2,4'(1H,3'H)-dione and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.