4-(4-Nitrophenyl)-2-(4-phenylpiperazin-1-yl)-1,3-thiazole
TL;DR: 4-(4-Nitrophenyl)-2-(4-phenylpiperazin-1-yl)-1,3-thiazole (CAS 345987-65-7) is a chemical compound with molecular formula C19H18N4O2S and molecular weight 366.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-(4-nitrophenyl)-2-(4-phenylpiperazin-1-yl)-1,3-thiazole
Also Known As: 4-(4-nitrophenyl)-2-(4-phenylpiperazin-1-yl)-1,3-thiazole, 4-(4-nitrophenyl)-2-(4-phenylpiperazinyl)-1,3-thiazole, 1-[4-(4-nitrophenyl)-1,3-thiazol-2-yl]-4-phenylpiperazine
| Molecular Formula | C19H18N4O2S |
|---|---|
| Molecular Weight | 366.12 g/mol |
| LogP | 4.0449 |
| Topological Polar Surface Area | 62.51 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 4 |
| Exact Mass | 366.11505 |
| Heavy Atoms | 26 |
| Complexity | 887.4173 |
Chemical Identifiers
| CAS Number | 345987-65-7 |
|---|---|
| SMILES | C1CN(CCN1C2=CC=CC=C2)C3=NC(=CS3)C4=CC=C(C=C4)[N+](=O)[O-] |
Product Overview
4-(4-Nitrophenyl)-2-(4-phenylpiperazin-1-yl)-1,3-thiazole (CAS 345987-65-7), with molecular formula C19H18N4O2S and molecular weight 366.12 g/mol. IUPAC: 4-(4-nitrophenyl)-2-(4-phenylpiperazin-1-yl)-1,3-thiazole.
Chemical Property Profile of 4-(4-Nitrophenyl)-2-(4-phenylpiperazin-1-yl)-1,3-thiazole
Property Insights of 4-(4-Nitrophenyl)-2-(4-phenylpiperazin-1-yl)-1,3-thiazole
The XLogP value of 4.0449 indicates that 4-(4-Nitrophenyl)-2-(4-phenylpiperazin-1-yl)-1,3-thiazole is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 62.51 Ų falls within the moderate polarity range, balancing permeability and solubility for 4-(4-Nitrophenyl)-2-(4-phenylpiperazin-1-yl)-1,3-thiazole. Following Lipinski's Rule of Five, 4-(4-Nitrophenyl)-2-(4-phenylpiperazin-1-yl)-1,3-thiazole has 0 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-(4-Nitrophenyl)-2-(4-phenylpiperazin-1-yl)-1,3-thiazole?
The CAS number of 4-(4-Nitrophenyl)-2-(4-phenylpiperazin-1-yl)-1,3-thiazole is 345987-65-7.
What is the molecular formula of 4-(4-Nitrophenyl)-2-(4-phenylpiperazin-1-yl)-1,3-thiazole?
The molecular formula of 4-(4-Nitrophenyl)-2-(4-phenylpiperazin-1-yl)-1,3-thiazole is C19H18N4O2S.
What is the molecular weight of 4-(4-Nitrophenyl)-2-(4-phenylpiperazin-1-yl)-1,3-thiazole?
The molecular weight of 4-(4-Nitrophenyl)-2-(4-phenylpiperazin-1-yl)-1,3-thiazole is 366.12 g/mol.
Where can I buy 4-(4-Nitrophenyl)-2-(4-phenylpiperazin-1-yl)-1,3-thiazole?
You can request a quote for 4-(4-Nitrophenyl)-2-(4-phenylpiperazin-1-yl)-1,3-thiazole directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-(4-Nitrophenyl)-2-(4-phenylpiperazin-1-yl)-1,3-thiazole?
Yes, KEHONG BIO provides custom synthesis services for 4-(4-Nitrophenyl)-2-(4-phenylpiperazin-1-yl)-1,3-thiazole and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.