![4-[2-(trimethylsilyl)ethynyl]-2H-chromen-2-one structure](/static/products/345/345949-07-7.png)
4-[2-(trimethylsilyl)ethynyl]-2H-chromen-2-one
TL;DR: 4-[2-(trimethylsilyl)ethynyl]-2H-chromen-2-one (CAS 345949-07-7) is a chemical compound with molecular formula C14H14O2Si and molecular weight 242.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-(2-trimethylsilylethynyl)chromen-2-one
Also Known As: 4-(Trimethylsilylethynyl)coumarin, ICCB4_000179, 4-[2-(trimethylsilyl)ethynyl]-2H-chromen-2-one, 4-(2-trimethylsilylethynyl)chromen-2-one, J1.538.520K
| Molecular Formula | C14H14O2Si |
|---|---|
| Molecular Weight | 242.08 g/mol |
| LogP | 3.0219 |
| Topological Polar Surface Area | 30.21 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 0 |
| Exact Mass | 242.07631 |
| Heavy Atoms | 17 |
| Complexity | 666.1524 |
Chemical Identifiers
| CAS Number | 345949-07-7 |
|---|---|
| SMILES | C[Si](C)(C)C#CC1=CC(=O)OC2=CC=CC=C21 |
Product Overview
4-[2-(trimethylsilyl)ethynyl]-2H-chromen-2-one (CAS 345949-07-7), with molecular formula C14H14O2Si and molecular weight 242.08 g/mol. IUPAC: 4-(2-trimethylsilylethynyl)chromen-2-one.
Chemical Property Profile of 4-[2-(trimethylsilyl)ethynyl]-2H-chromen-2-one
Property Insights of 4-[2-(trimethylsilyl)ethynyl]-2H-chromen-2-one
The XLogP value of 3.0219 indicates that 4-[2-(trimethylsilyl)ethynyl]-2H-chromen-2-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 30.21 Ų, 4-[2-(trimethylsilyl)ethynyl]-2H-chromen-2-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-[2-(trimethylsilyl)ethynyl]-2H-chromen-2-one has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-[2-(trimethylsilyl)ethynyl]-2H-chromen-2-one?
The CAS number of 4-[2-(trimethylsilyl)ethynyl]-2H-chromen-2-one is 345949-07-7.
What is the molecular formula of 4-[2-(trimethylsilyl)ethynyl]-2H-chromen-2-one?
The molecular formula of 4-[2-(trimethylsilyl)ethynyl]-2H-chromen-2-one is C14H14O2Si.
What is the molecular weight of 4-[2-(trimethylsilyl)ethynyl]-2H-chromen-2-one?
The molecular weight of 4-[2-(trimethylsilyl)ethynyl]-2H-chromen-2-one is 242.08 g/mol.
Where can I buy 4-[2-(trimethylsilyl)ethynyl]-2H-chromen-2-one?
You can request a quote for 4-[2-(trimethylsilyl)ethynyl]-2H-chromen-2-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-[2-(trimethylsilyl)ethynyl]-2H-chromen-2-one?
Yes, KEHONG BIO provides custom synthesis services for 4-[2-(trimethylsilyl)ethynyl]-2H-chromen-2-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.