AF-399/15128470
TL;DR: AF-399/15128470 (CAS 345615-60-3) is a chemical compound with molecular formula C15H11ClF3N3S and molecular weight 357.03 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[4-chloro-3-(trifluoromethyl)phenyl]-5,6-dimethylthieno[2,3-d]pyrimidin-4-amine
Also Known As: AF-399/15128470, N-[4-chloro-3-(trifluoromethyl)phenyl]-5,6-dimethylthieno[2,3-d]pyrimidin-4-amine, (5,6-dimethylthiopheno[3,2-e]pyrimidin-4-yl)[4-chloro-3-(trifluoromethyl)pheny l]amine
| Molecular Formula | C15H11ClF3N3S |
|---|---|
| Molecular Weight | 357.03 g/mol |
| LogP | 5.72394 |
| Topological Polar Surface Area | 37.81 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Exact Mass | 357.03143 |
| Heavy Atoms | 23 |
| Complexity | 889.53986 |
Chemical Identifiers
| CAS Number | 345615-60-3 |
|---|---|
| SMILES | CC1=C(SC2=NC=NC(=C12)NC3=CC(=C(C=C3)Cl)C(F)(F)F)C |
Product Overview
AF-399/15128470 (CAS 345615-60-3), with molecular formula C15H11ClF3N3S and molecular weight 357.03 g/mol. IUPAC: N-[4-chloro-3-(trifluoromethyl)phenyl]-5,6-dimethylthieno[2,3-d]pyrimidin-4-amine.
Chemical Property Profile of AF-399/15128470
Property Insights of AF-399/15128470
The XLogP value of 5.72394 indicates that AF-399/15128470 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 37.81 Ų, AF-399/15128470 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, AF-399/15128470 has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of AF-399/15128470?
The CAS number of AF-399/15128470 is 345615-60-3.
What is the molecular formula of AF-399/15128470?
The molecular formula of AF-399/15128470 is C15H11ClF3N3S.
What is the molecular weight of AF-399/15128470?
The molecular weight of AF-399/15128470 is 357.03 g/mol.
Where can I buy AF-399/15128470?
You can request a quote for AF-399/15128470 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for AF-399/15128470?
Yes, KEHONG BIO provides custom synthesis services for AF-399/15128470 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.