![3-methyl-1-[3-(trifluoromethyl)phenyl]-1H-pyrazol-5-amine structure](/static/products/3450/345-07-3.webp)
3-methyl-1-[3-(trifluoromethyl)phenyl]-1H-pyrazol-5-amine
TL;DR: 3-methyl-1-[3-(trifluoromethyl)phenyl]-1H-pyrazol-5-amine (CAS 345-07-3) is a chemical compound with molecular formula C11H10F3N3 and molecular weight 241.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-methyl-2-[3-(trifluoromethyl)phenyl]pyrazol-3-amine
Also Known As: Rubitecan, 3-Methyl-1-[3-(trifluoromethyl)phenyl]-1H-pyrazol-5-amine, 5-Methyl-2-(3-trifluoromethyl-phenyl)-2H-pyrazol-3-ylamine, 5-methyl-2-[3-(trifluoromethyl)phenyl]pyrazol-3-amine, 3-Methyl-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-5-amine
| Molecular Formula | C11H10F3N3 |
|---|---|
| Molecular Weight | 241.08 g/mol |
| LogP | 2.78172 |
| Topological Polar Surface Area | 43.84 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 1 |
| Exact Mass | 241.08269 |
| Heavy Atoms | 17 |
| Complexity | 543.13495 |
Chemical Identifiers
| CAS Number | 345-07-3 |
|---|---|
| SMILES | CC1=NN(C(=C1)N)C2=CC=CC(=C2)C(F)(F)F |
Product Overview
3-methyl-1-[3-(trifluoromethyl)phenyl]-1H-pyrazol-5-amine (CAS 345-07-3), with molecular formula C11H10F3N3 and molecular weight 241.08 g/mol. IUPAC: 5-methyl-2-[3-(trifluoromethyl)phenyl]pyrazol-3-amine.
Chemical Property Profile of 3-methyl-1-[3-(trifluoromethyl)phenyl]-1H-pyrazol-5-amine
Property Insights of 3-methyl-1-[3-(trifluoromethyl)phenyl]-1H-pyrazol-5-amine
The XLogP value of 2.78172 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 3-methyl-1-[3-(trifluoromethyl)phenyl]-1H-pyrazol-5-amine. With a topological polar surface area (TPSA) of 43.84 Ų, 3-methyl-1-[3-(trifluoromethyl)phenyl]-1H-pyrazol-5-amine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 3-methyl-1-[3-(trifluoromethyl)phenyl]-1H-pyrazol-5-amine has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 3-methyl-1-[3-(trifluoromethyl)phenyl]-1H-pyrazol-5-amine?
The CAS number of 3-methyl-1-[3-(trifluoromethyl)phenyl]-1H-pyrazol-5-amine is 345-07-3.
What is the molecular formula of 3-methyl-1-[3-(trifluoromethyl)phenyl]-1H-pyrazol-5-amine?
The molecular formula of 3-methyl-1-[3-(trifluoromethyl)phenyl]-1H-pyrazol-5-amine is C11H10F3N3.
What is the molecular weight of 3-methyl-1-[3-(trifluoromethyl)phenyl]-1H-pyrazol-5-amine?
The molecular weight of 3-methyl-1-[3-(trifluoromethyl)phenyl]-1H-pyrazol-5-amine is 241.08 g/mol.
Where can I buy 3-methyl-1-[3-(trifluoromethyl)phenyl]-1H-pyrazol-5-amine?
You can request a quote for 3-methyl-1-[3-(trifluoromethyl)phenyl]-1H-pyrazol-5-amine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 3-methyl-1-[3-(trifluoromethyl)phenyl]-1H-pyrazol-5-amine?
Yes, KEHONG BIO provides custom synthesis services for 3-methyl-1-[3-(trifluoromethyl)phenyl]-1H-pyrazol-5-amine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.