4-(4-Chlorophenyl)-2-(4-fluorophenyl)-4-oxobutanenitrile structure

4-(4-Chlorophenyl)-2-(4-fluorophenyl)-4-oxobutanenitrile

TL;DR: 4-(4-Chlorophenyl)-2-(4-fluorophenyl)-4-oxobutanenitrile (CAS 344280-72-4) is a chemical compound with molecular formula C16H11ClFNO and molecular weight 287.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

4-(4-chlorophenyl)-2-(4-fluorophenyl)-4-oxobutanenitrile

Also Known As: 4-(4-chlorophenyl)-2-(4-fluorophenyl)-4-oxobutanenitrile, 7J-547S, 4-(4-chlorophenyl)-2-(4-fluorophenyl)-4-oxo-butanenitrile

CAS: 344280-72-4
Molecular Formula C16H11ClFNO
Molecular Weight 287.05 g/mol
LogP 4.35928
Topological Polar Surface Area 40.86 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 2
Rotatable Bonds 4
Exact Mass 287.05133
Heavy Atoms 20
Complexity 643.67224

Chemical Identifiers

CAS Number 344280-72-4
SMILES C1=CC(=CC=C1C(CC(=O)C2=CC=C(C=C2)Cl)C#N)F

Product Overview

4-(4-Chlorophenyl)-2-(4-fluorophenyl)-4-oxobutanenitrile (CAS 344280-72-4), with molecular formula C16H11ClFNO and molecular weight 287.05 g/mol. IUPAC: 4-(4-chlorophenyl)-2-(4-fluorophenyl)-4-oxobutanenitrile.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 4-(4-Chlorophenyl)-2-(4-fluorophenyl)-4-oxobutanenitrile

XLogP
4.35928
TPSA (Topological Polar Surface Area)
40.86
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
2
Rotatable Bonds
4
Heavy Atoms
20
Complexity
643.67224
Exact Mass
287.05133
Monoisotopic Mass
287.05133
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 4-(4-Chlorophenyl)-2-(4-fluorophenyl)-4-oxobutanenitrile

The XLogP value of 4.35928 indicates that 4-(4-Chlorophenyl)-2-(4-fluorophenyl)-4-oxobutanenitrile is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 40.86 Ų, 4-(4-Chlorophenyl)-2-(4-fluorophenyl)-4-oxobutanenitrile exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-(4-Chlorophenyl)-2-(4-fluorophenyl)-4-oxobutanenitrile has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 4-(4-Chlorophenyl)-2-(4-fluorophenyl)-4-oxobutanenitrile?

The CAS number of 4-(4-Chlorophenyl)-2-(4-fluorophenyl)-4-oxobutanenitrile is 344280-72-4.

What is the molecular formula of 4-(4-Chlorophenyl)-2-(4-fluorophenyl)-4-oxobutanenitrile?

The molecular formula of 4-(4-Chlorophenyl)-2-(4-fluorophenyl)-4-oxobutanenitrile is C16H11ClFNO.

What is the molecular weight of 4-(4-Chlorophenyl)-2-(4-fluorophenyl)-4-oxobutanenitrile?

The molecular weight of 4-(4-Chlorophenyl)-2-(4-fluorophenyl)-4-oxobutanenitrile is 287.05 g/mol.

Where can I buy 4-(4-Chlorophenyl)-2-(4-fluorophenyl)-4-oxobutanenitrile?

You can request a quote for 4-(4-Chlorophenyl)-2-(4-fluorophenyl)-4-oxobutanenitrile directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 4-(4-Chlorophenyl)-2-(4-fluorophenyl)-4-oxobutanenitrile?

Yes, KEHONG BIO provides custom synthesis services for 4-(4-Chlorophenyl)-2-(4-fluorophenyl)-4-oxobutanenitrile and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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