7H-072
TL;DR: 7H-072 (CAS 344263-52-1) is a chemical compound with molecular formula C23H17Cl2F3N2O and molecular weight 464.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(4-chlorophenyl)-[1-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]methyl]-3,4-dihydro-1H-isoquinolin-2-yl]methanone
Also Known As: 7H-072, (4-Chlorophenyl)(1-((3-chloro-5-(trifluoromethyl)-2-pyridinyl)methyl)-3,4-dihydro-2(1H)-isoquinolinyl)methanone, (4-chlorophenyl)-[1-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]-3,4-dihydro-1H-isoquinolin-2-yl]methanone, 1-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl}-2-(4-chlorobenzoyl)-1,2,3,4-tetrahydroisoquinoline, (4-CHLOROPHENYL)[1-([3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]METHYL)-3,4-DIHYDRO-2(1H)-ISOQUINOLINYL]METHANONE
| Molecular Formula | C23H17Cl2F3N2O |
|---|---|
| Molecular Weight | 464.07 g/mol |
| LogP | 6.3895 |
| Topological Polar Surface Area | 33.2 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 3 |
| Exact Mass | 464.06702 |
| Heavy Atoms | 31 |
| Complexity | 1116.5496 |
Chemical Identifiers
| CAS Number | 344263-52-1 |
|---|---|
| SMILES | C1CN(C(C2=CC=CC=C21)CC3=C(C=C(C=N3)C(F)(F)F)Cl)C(=O)C4=CC=C(C=C4)Cl |
Product Overview
7H-072 (CAS 344263-52-1), with molecular formula C23H17Cl2F3N2O and molecular weight 464.07 g/mol. IUPAC: (4-chlorophenyl)-[1-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]methyl]-3,4-dihydro-1H-isoquinolin-2-yl]methanone.
Chemical Property Profile of 7H-072
Property Insights of 7H-072
The XLogP value of 6.3895 indicates that 7H-072 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 33.2 Ų, 7H-072 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 7H-072 has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 7H-072?
The CAS number of 7H-072 is 344263-52-1.
What is the molecular formula of 7H-072?
The molecular formula of 7H-072 is C23H17Cl2F3N2O.
What is the molecular weight of 7H-072?
The molecular weight of 7H-072 is 464.07 g/mol.
Where can I buy 7H-072?
You can request a quote for 7H-072 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 7H-072?
Yes, KEHONG BIO provides custom synthesis services for 7H-072 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.