3-O-Methyl Estradiol structure

3-O-Methyl Estradiol

TL;DR: 3-O-Methyl Estradiol (CAS 3434-76-2) is a chemical compound with molecular formula C19H26O2 and molecular weight 286.19 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(8S,9S,13S,14R,17R)-3-methoxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-ol

Also Known As: 3-O-Methyl Estradiol, 3-O-Methyl 17a-Estradiol

CAS: 3434-76-2
Molecular Formula C19H26O2
Molecular Weight 286.19 g/mol
LogP 3.9122
Topological Polar Surface Area 29.46 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 2
Rotatable Bonds 1
Exact Mass 286.19327
Heavy Atoms 21
Complexity 552.4974

Chemical Identifiers

CAS Number 3434-76-2
SMILES C[C@]12CC[C@H]3[C@@H]([C@H]1CC[C@H]2O)CCC4=C3C=CC(=C4)OC

Product Overview

3-O-Methyl Estradiol (CAS 3434-76-2), with molecular formula C19H26O2 and molecular weight 286.19 g/mol. IUPAC: (8S,9S,13S,14R,17R)-3-methoxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-ol.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of 3-O-Methyl Estradiol

XLogP
3.9122
TPSA (Topological Polar Surface Area)
29.46
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
2
Rotatable Bonds
1
Heavy Atoms
21
Complexity
552.4974
Exact Mass
286.19327
Monoisotopic Mass
286.19327
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 3-O-Methyl Estradiol

The XLogP value of 3.9122 indicates that 3-O-Methyl Estradiol is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 29.46 Ų, 3-O-Methyl Estradiol exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 3-O-Methyl Estradiol has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 3-O-Methyl Estradiol?

The CAS number of 3-O-Methyl Estradiol is 3434-76-2.

What is the molecular formula of 3-O-Methyl Estradiol?

The molecular formula of 3-O-Methyl Estradiol is C19H26O2.

What is the molecular weight of 3-O-Methyl Estradiol?

The molecular weight of 3-O-Methyl Estradiol is 286.19 g/mol.

Where can I buy 3-O-Methyl Estradiol?

You can request a quote for 3-O-Methyl Estradiol directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 3-O-Methyl Estradiol?

Yes, KEHONG BIO provides custom synthesis services for 3-O-Methyl Estradiol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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