4-(4-Chlorophenyl)-2-oxo-5-(phenylmethylene)-2,5-dihydro-3-furancarbonitrile
TL;DR: 4-(4-Chlorophenyl)-2-oxo-5-(phenylmethylene)-2,5-dihydro-3-furancarbonitrile (CAS 343375-81-5) is a chemical compound with molecular formula C18H10ClNO2 and molecular weight 307.04 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(5Z)-5-benzylidene-4-(4-chlorophenyl)-2-oxofuran-3-carbonitrile
Also Known As: 4-(4-chlorophenyl)-2-oxo-5-(phenylmethylene)-2,5-dihydro-3-furancarbonitrile, (5Z)-4-(4-chlorophenyl)-2-oxo-5-(phenylmethylidene)-2,5-dihydrofuran-3-carbonitrile, (5Z)-5-benzylidene-4-(4-chlorophenyl)-2-oxofuran-3-carbonitrile, 5-benzylidene-4-(4-chlorophenyl)-2-oxofuran-3-carbonitrile, (5Z)-5-benzylidene-4-(4-chlorophenyl)-2-oxo-furan-3-carbonitrile
| Molecular Formula | C18H10ClNO2 |
|---|---|
| Molecular Weight | 307.04 g/mol |
| LogP | 4.21508 |
| Topological Polar Surface Area | 50.09 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 307.04 |
| Heavy Atoms | 22 |
| Complexity | 827.6409 |
Chemical Identifiers
| CAS Number | 343375-81-5 |
|---|---|
| SMILES | C1=CC=C(C=C1)/C=C\2/C(=C(C(=O)O2)C#N)C3=CC=C(C=C3)Cl |
Product Overview
4-(4-Chlorophenyl)-2-oxo-5-(phenylmethylene)-2,5-dihydro-3-furancarbonitrile (CAS 343375-81-5), with molecular formula C18H10ClNO2 and molecular weight 307.04 g/mol. IUPAC: (5Z)-5-benzylidene-4-(4-chlorophenyl)-2-oxofuran-3-carbonitrile.
Chemical Property Profile of 4-(4-Chlorophenyl)-2-oxo-5-(phenylmethylene)-2,5-dihydro-3-furancarbonitrile
Property Insights of 4-(4-Chlorophenyl)-2-oxo-5-(phenylmethylene)-2,5-dihydro-3-furancarbonitrile
The XLogP value of 4.21508 indicates that 4-(4-Chlorophenyl)-2-oxo-5-(phenylmethylene)-2,5-dihydro-3-furancarbonitrile is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 50.09 Ų, 4-(4-Chlorophenyl)-2-oxo-5-(phenylmethylene)-2,5-dihydro-3-furancarbonitrile exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-(4-Chlorophenyl)-2-oxo-5-(phenylmethylene)-2,5-dihydro-3-furancarbonitrile has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-(4-Chlorophenyl)-2-oxo-5-(phenylmethylene)-2,5-dihydro-3-furancarbonitrile?
The CAS number of 4-(4-Chlorophenyl)-2-oxo-5-(phenylmethylene)-2,5-dihydro-3-furancarbonitrile is 343375-81-5.
What is the molecular formula of 4-(4-Chlorophenyl)-2-oxo-5-(phenylmethylene)-2,5-dihydro-3-furancarbonitrile?
The molecular formula of 4-(4-Chlorophenyl)-2-oxo-5-(phenylmethylene)-2,5-dihydro-3-furancarbonitrile is C18H10ClNO2.
What is the molecular weight of 4-(4-Chlorophenyl)-2-oxo-5-(phenylmethylene)-2,5-dihydro-3-furancarbonitrile?
The molecular weight of 4-(4-Chlorophenyl)-2-oxo-5-(phenylmethylene)-2,5-dihydro-3-furancarbonitrile is 307.04 g/mol.
Where can I buy 4-(4-Chlorophenyl)-2-oxo-5-(phenylmethylene)-2,5-dihydro-3-furancarbonitrile?
You can request a quote for 4-(4-Chlorophenyl)-2-oxo-5-(phenylmethylene)-2,5-dihydro-3-furancarbonitrile directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-(4-Chlorophenyl)-2-oxo-5-(phenylmethylene)-2,5-dihydro-3-furancarbonitrile?
Yes, KEHONG BIO provides custom synthesis services for 4-(4-Chlorophenyl)-2-oxo-5-(phenylmethylene)-2,5-dihydro-3-furancarbonitrile and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.