N-(4-fluorophenyl)-2-(2-hydroxybenzoyl)hydrazinecarbothioamide
TL;DR: N-(4-fluorophenyl)-2-(2-hydroxybenzoyl)hydrazinecarbothioamide (CAS 343-70-4) is a chemical compound with molecular formula C14H12FN3O2S and molecular weight 305.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-(4-fluorophenyl)-3-[(2-hydroxybenzoyl)amino]thiourea
Also Known As: BAS 01176013, N-(4-fluorophenyl)-2-(2-hydroxybenzoyl)hydrazinecarbothioamide, 1-(4-fluorophenyl)-3-[(2-hydroxybenzoyl)amino]thiourea, AN-329/40396900, 4-(4-fluoro-phenyl)-1-salicyloyl thiosemicarbazide
| Molecular Formula | C14H12FN3O2S |
|---|---|
| Molecular Weight | 305.06 g/mol |
| LogP | 3.0 |
| Topological Polar Surface Area | 105.0 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Exact Mass | 305.06342 |
| Heavy Atoms | 21 |
| Complexity | 375.0 |
Chemical Identifiers
| CAS Number | 343-70-4 |
|---|---|
| SMILES | C1=CC=C(C(=C1)C(=O)NNC(=S)NC2=CC=C(C=C2)F)O |
| InChIKey | HAWQFTQKDAUJNE-UHFFFAOYSA-N |
Product Overview
N-(4-fluorophenyl)-2-(2-hydroxybenzoyl)hydrazinecarbothioamide (CAS 343-70-4), with molecular formula C14H12FN3O2S and molecular weight 305.06 g/mol. IUPAC: 1-(4-fluorophenyl)-3-[(2-hydroxybenzoyl)amino]thiourea.
Chemical Property Profile of N-(4-fluorophenyl)-2-(2-hydroxybenzoyl)hydrazinecarbothioamide
Property Insights of N-(4-fluorophenyl)-2-(2-hydroxybenzoyl)hydrazinecarbothioamide
The XLogP value of 3.0 indicates that N-(4-fluorophenyl)-2-(2-hydroxybenzoyl)hydrazinecarbothioamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 105.0 Ų falls within the moderate polarity range, balancing permeability and solubility for N-(4-fluorophenyl)-2-(2-hydroxybenzoyl)hydrazinecarbothioamide. Following Lipinski's Rule of Five, N-(4-fluorophenyl)-2-(2-hydroxybenzoyl)hydrazinecarbothioamide has 4 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-(4-fluorophenyl)-2-(2-hydroxybenzoyl)hydrazinecarbothioamide?
The CAS number of N-(4-fluorophenyl)-2-(2-hydroxybenzoyl)hydrazinecarbothioamide is 343-70-4.
What is the molecular formula of N-(4-fluorophenyl)-2-(2-hydroxybenzoyl)hydrazinecarbothioamide?
The molecular formula of N-(4-fluorophenyl)-2-(2-hydroxybenzoyl)hydrazinecarbothioamide is C14H12FN3O2S.
What is the molecular weight of N-(4-fluorophenyl)-2-(2-hydroxybenzoyl)hydrazinecarbothioamide?
The molecular weight of N-(4-fluorophenyl)-2-(2-hydroxybenzoyl)hydrazinecarbothioamide is 305.06 g/mol.
Where can I buy N-(4-fluorophenyl)-2-(2-hydroxybenzoyl)hydrazinecarbothioamide?
You can request a quote for N-(4-fluorophenyl)-2-(2-hydroxybenzoyl)hydrazinecarbothioamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-(4-fluorophenyl)-2-(2-hydroxybenzoyl)hydrazinecarbothioamide?
Yes, KEHONG BIO provides custom synthesis services for N-(4-fluorophenyl)-2-(2-hydroxybenzoyl)hydrazinecarbothioamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.