AF-399/14738016
TL;DR: AF-399/14738016 (CAS 342779-33-3) is a chemical compound with molecular formula C16H21F3N2O3S2 and molecular weight 410.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(1-thiophen-2-ylsulfonylpiperidin-4-yl)-[3-(trifluoromethyl)piperidin-1-yl]methanone
Also Known As: AF-399/14738016, (1-(thiophen-2-ylsulfonyl)piperidin-4-yl)(3-(trifluoromethyl)piperidin-1-yl)methanone, F0727-0018, (1-thiophen-2-ylsulfonylpiperidin-4-yl)-[3-(trifluoromethyl)piperidin-1-yl]methanone, 1-[1-(thiophene-2-sulfonyl)piperidine-4-carbonyl]-3-(trifluoromethyl)piperidine
| Molecular Formula | C16H21F3N2O3S2 |
|---|---|
| Molecular Weight | 410.09 g/mol |
| LogP | 2.9497 |
| Topological Polar Surface Area | 57.69 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 410.09457 |
| Heavy Atoms | 26 |
| Complexity | 726.42114 |
Chemical Identifiers
| CAS Number | 342779-33-3 |
|---|---|
| SMILES | C1CC(CN(C1)C(=O)C2CCN(CC2)S(=O)(=O)C3=CC=CS3)C(F)(F)F |
Product Overview
AF-399/14738016 (CAS 342779-33-3), with molecular formula C16H21F3N2O3S2 and molecular weight 410.09 g/mol. IUPAC: (1-thiophen-2-ylsulfonylpiperidin-4-yl)-[3-(trifluoromethyl)piperidin-1-yl]methanone.
Chemical Property Profile of AF-399/14738016
Property Insights of AF-399/14738016
The XLogP value of 2.9497 suggests moderate lipophilicity, balancing water solubility and membrane permeability for AF-399/14738016. With a topological polar surface area (TPSA) of 57.69 Ų, AF-399/14738016 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, AF-399/14738016 has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of AF-399/14738016?
The CAS number of AF-399/14738016 is 342779-33-3.
What is the molecular formula of AF-399/14738016?
The molecular formula of AF-399/14738016 is C16H21F3N2O3S2.
What is the molecular weight of AF-399/14738016?
The molecular weight of AF-399/14738016 is 410.09 g/mol.
Where can I buy AF-399/14738016?
You can request a quote for AF-399/14738016 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for AF-399/14738016?
Yes, KEHONG BIO provides custom synthesis services for AF-399/14738016 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.