10L-348S
TL;DR: 10L-348S (CAS 341964-96-3) is a chemical compound with molecular formula C22H16Cl2F3N3 and molecular weight 449.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-(2,4-dichlorophenyl)-2-(propan-2-ylamino)-6-[3-(trifluoromethyl)phenyl]pyridine-3-carbonitrile
Also Known As: 10L-348S, 4-(2,4-dichlorophenyl)-2-(isopropylamino)-6-[3-(trifluoromethyl)phenyl]nicotinonitrile, 4-(2,4-dichlorophenyl)-2-(propan-2-ylamino)-6-[3-(trifluoromethyl)phenyl]pyridine-3-carbonitrile, 4-(2,4-dichlorophenyl)-2-[(propan-2-yl)amino]-6-[3-(trifluoromethyl)phenyl]pyridine-3-carbonitrile
| Molecular Formula | C22H16Cl2F3N3 |
|---|---|
| Molecular Weight | 449.07 g/mol |
| LogP | 7.43318 |
| Topological Polar Surface Area | 48.71 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 4 |
| Exact Mass | 449.06735 |
| Heavy Atoms | 30 |
| Complexity | 1135.4473 |
Chemical Identifiers
| CAS Number | 341964-96-3 |
|---|---|
| SMILES | CC(C)NC1=C(C(=CC(=N1)C2=CC(=CC=C2)C(F)(F)F)C3=C(C=C(C=C3)Cl)Cl)C#N |
Product Overview
10L-348S (CAS 341964-96-3), with molecular formula C22H16Cl2F3N3 and molecular weight 449.07 g/mol. IUPAC: 4-(2,4-dichlorophenyl)-2-(propan-2-ylamino)-6-[3-(trifluoromethyl)phenyl]pyridine-3-carbonitrile.
Chemical Property Profile of 10L-348S
Property Insights of 10L-348S
The XLogP value of 7.43318 indicates that 10L-348S is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 48.71 Ų, 10L-348S exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 10L-348S has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 10L-348S?
The CAS number of 10L-348S is 341964-96-3.
What is the molecular formula of 10L-348S?
The molecular formula of 10L-348S is C22H16Cl2F3N3.
What is the molecular weight of 10L-348S?
The molecular weight of 10L-348S is 449.07 g/mol.
Where can I buy 10L-348S?
You can request a quote for 10L-348S directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 10L-348S?
Yes, KEHONG BIO provides custom synthesis services for 10L-348S and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.