6-(2-Chlorophenyl)-2-hydroxy-4-(4-methylphenyl)nicotinonitrile
TL;DR: 6-(2-Chlorophenyl)-2-hydroxy-4-(4-methylphenyl)nicotinonitrile (CAS 341964-46-3) is a chemical compound with molecular formula C19H13ClN2O and molecular weight 320.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
6-(2-chlorophenyl)-4-(4-methylphenyl)-2-oxo-1H-pyridine-3-carbonitrile
Also Known As: 6-(2-chlorophenyl)-2-hydroxy-4-(4-methylphenyl)nicotinonitrile, 10L-312S, 6-(2-chlorophenyl)-2-hydroxy-4-(4-methylphenyl)pyridine-3-carbonitrile, 6-(2-chlorophenyl)-4-(4-methylphenyl)-2-oxo-1H-pyridine-3-carbonitrile, 6-(2-chlorophenyl)-2-oxo-4-(p-tolyl)-1H-pyridine-3-carbonitrile
| Molecular Formula | C19H13ClN2O |
|---|---|
| Molecular Weight | 320.07 g/mol |
| LogP | 4.5424 |
| Topological Polar Surface Area | 56.65 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 2 |
| Exact Mass | 320.07166 |
| Heavy Atoms | 23 |
| Complexity | 965.89514 |
Chemical Identifiers
| CAS Number | 341964-46-3 |
|---|---|
| SMILES | CC1=CC=C(C=C1)C2=C(C(=O)NC(=C2)C3=CC=CC=C3Cl)C#N |
Product Overview
6-(2-Chlorophenyl)-2-hydroxy-4-(4-methylphenyl)nicotinonitrile (CAS 341964-46-3), with molecular formula C19H13ClN2O and molecular weight 320.07 g/mol. IUPAC: 6-(2-chlorophenyl)-4-(4-methylphenyl)-2-oxo-1H-pyridine-3-carbonitrile.
Chemical Property Profile of 6-(2-Chlorophenyl)-2-hydroxy-4-(4-methylphenyl)nicotinonitrile
Property Insights of 6-(2-Chlorophenyl)-2-hydroxy-4-(4-methylphenyl)nicotinonitrile
The XLogP value of 4.5424 indicates that 6-(2-Chlorophenyl)-2-hydroxy-4-(4-methylphenyl)nicotinonitrile is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 56.65 Ų, 6-(2-Chlorophenyl)-2-hydroxy-4-(4-methylphenyl)nicotinonitrile exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 6-(2-Chlorophenyl)-2-hydroxy-4-(4-methylphenyl)nicotinonitrile has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 6-(2-Chlorophenyl)-2-hydroxy-4-(4-methylphenyl)nicotinonitrile?
The CAS number of 6-(2-Chlorophenyl)-2-hydroxy-4-(4-methylphenyl)nicotinonitrile is 341964-46-3.
What is the molecular formula of 6-(2-Chlorophenyl)-2-hydroxy-4-(4-methylphenyl)nicotinonitrile?
The molecular formula of 6-(2-Chlorophenyl)-2-hydroxy-4-(4-methylphenyl)nicotinonitrile is C19H13ClN2O.
What is the molecular weight of 6-(2-Chlorophenyl)-2-hydroxy-4-(4-methylphenyl)nicotinonitrile?
The molecular weight of 6-(2-Chlorophenyl)-2-hydroxy-4-(4-methylphenyl)nicotinonitrile is 320.07 g/mol.
Where can I buy 6-(2-Chlorophenyl)-2-hydroxy-4-(4-methylphenyl)nicotinonitrile?
You can request a quote for 6-(2-Chlorophenyl)-2-hydroxy-4-(4-methylphenyl)nicotinonitrile directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 6-(2-Chlorophenyl)-2-hydroxy-4-(4-methylphenyl)nicotinonitrile?
Yes, KEHONG BIO provides custom synthesis services for 6-(2-Chlorophenyl)-2-hydroxy-4-(4-methylphenyl)nicotinonitrile and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.