17-Hydroxypregna-4,9(11)-diene-3,20-dione structure

17-Hydroxypregna-4,9(11)-diene-3,20-dione

TL;DR: 17-Hydroxypregna-4,9(11)-diene-3,20-dione (CAS 34184-82-2) is a chemical compound with molecular formula C21H28O3 and molecular weight 328.20 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(8S,10S,13S,14S,17R)-17-acetyl-17-hydroxy-10,13-dimethyl-2,6,7,8,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthren-3-one

Also Known As: 17-Hydroxypregna-4,9(11)-diene-3,20-dione, 21-Desacetoxy Anecortave, EC 251-868-4, (8S,10S,13S,14S,17R)-17-acetyl-17-hydroxy-10,13-dimethyl-2,6,7,8,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthren-3-one, Pregna-4,9(11)-diene-3,20-dione,17-hydroxy-

CAS: 34184-82-2
Molecular Formula C21H28O3
Molecular Weight 328.20 g/mol
LogP 2.1
Topological Polar Surface Area 54.4 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 3
Rotatable Bonds 1
Exact Mass 328.20386
Heavy Atoms 24
Complexity 687.0

Chemical Identifiers

CAS Number 34184-82-2
SMILES CC(=O)[C@]1(CC[C@@H]2[C@@]1(CC=C3[C@H]2CCC4=CC(=O)CC[C@@]43C)C)O
InChIKey ARJWMUSCDIJFLB-GVVDHYSOSA-N

Patent-Derived Application Labels

Derived from 3 IPC patent classification(s) across the SureChEMBL global patent database.

Catalysts (1 patents) Heterocyclic Building Blocks (32 patents) Pharmaceutical Intermediates (66 patents)

Product Overview

17-Hydroxypregna-4,9(11)-diene-3,20-dione (CAS 34184-82-2), with molecular formula C21H28O3 and molecular weight 328.20 g/mol. IUPAC: (8S,10S,13S,14S,17R)-17-acetyl-17-hydroxy-10,13-dimethyl-2,6,7,8,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthren-3-one.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 17-Hydroxypregna-4,9(11)-diene-3,20-dione

XLogP
2.1
TPSA (Topological Polar Surface Area)
54.4
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
3
Rotatable Bonds
1
Heavy Atoms
24
Complexity
687.0
Exact Mass
328.20386
Monoisotopic Mass
328.20386
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 17-Hydroxypregna-4,9(11)-diene-3,20-dione

The XLogP value of 2.1 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 17-Hydroxypregna-4,9(11)-diene-3,20-dione. With a topological polar surface area (TPSA) of 54.4 Ų, 17-Hydroxypregna-4,9(11)-diene-3,20-dione exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 17-Hydroxypregna-4,9(11)-diene-3,20-dione has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
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Frequently Asked Questions

What is the CAS number of 17-Hydroxypregna-4,9(11)-diene-3,20-dione?

The CAS number of 17-Hydroxypregna-4,9(11)-diene-3,20-dione is 34184-82-2.

What is the molecular formula of 17-Hydroxypregna-4,9(11)-diene-3,20-dione?

The molecular formula of 17-Hydroxypregna-4,9(11)-diene-3,20-dione is C21H28O3.

What is the molecular weight of 17-Hydroxypregna-4,9(11)-diene-3,20-dione?

The molecular weight of 17-Hydroxypregna-4,9(11)-diene-3,20-dione is 328.20 g/mol.

Where can I buy 17-Hydroxypregna-4,9(11)-diene-3,20-dione?

You can request a quote for 17-Hydroxypregna-4,9(11)-diene-3,20-dione directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 17-Hydroxypregna-4,9(11)-diene-3,20-dione?

Yes, KEHONG BIO provides custom synthesis services for 17-Hydroxypregna-4,9(11)-diene-3,20-dione and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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