Propafenone Hydrochloride
TL;DR: Propafenone Hydrochloride (CAS 34183-22-7) is a chemical compound with molecular formula C21H28ClNO3 and molecular weight 377.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[2-[2-hydroxy-3-(propylamino)propoxy]phenyl]-3-phenylpropan-1-one;hydrochloride
Also Known As: PROPAFENONE HYDROCHLORIDE, Propafenone HCl, Rythmol, Rytmonorm, Arythmol
| Molecular Formula | C21H28ClNO3 |
|---|---|
| Molecular Weight | 377.18 g/mol |
| LogP | 3.66 |
| Topological Polar Surface Area | 58.6 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 11 |
| Exact Mass | 377.17578 |
| Heavy Atoms | 26 |
| Complexity | 368.0 |
| Solubility | >56.7 [ug/mL] (The mean of the results at pH 7.4) |
Chemical Identifiers
| CAS Number | 34183-22-7 |
|---|---|
| SMILES | CCCNCC(COC1=CC=CC=C1C(=O)CCC2=CC=CC=C2)O.Cl |
| InChIKey | XWIHRGFIPXWGEF-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 19 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Propafenone Hydrochloride (CAS 34183-22-7), with molecular formula C21H28ClNO3 and molecular weight 377.18 g/mol. IUPAC: 1-[2-[2-hydroxy-3-(propylamino)propoxy]phenyl]-3-phenylpropan-1-one;hydrochloride.
Chemical Property Profile of Propafenone Hydrochloride
Property Insights of Propafenone Hydrochloride
The XLogP value of 3.66 indicates that Propafenone Hydrochloride is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 58.6 Ų, Propafenone Hydrochloride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Propafenone Hydrochloride has 3 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Propafenone Hydrochloride?
The CAS number of Propafenone Hydrochloride is 34183-22-7.
What is the molecular formula of Propafenone Hydrochloride?
The molecular formula of Propafenone Hydrochloride is C21H28ClNO3.
What is the molecular weight of Propafenone Hydrochloride?
The molecular weight of Propafenone Hydrochloride is 377.18 g/mol.
Where can I buy Propafenone Hydrochloride?
You can request a quote for Propafenone Hydrochloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Propafenone Hydrochloride?
Yes, KEHONG BIO provides custom synthesis services for Propafenone Hydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.