KDR-5169 free base
TL;DR: KDR-5169 free base (CAS 340984-78-3) is a chemical compound with molecular formula C22H27ClFN3O4 and molecular weight 451.17 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-amino-5-chloro-N-[1-[(3-fluoro-4-methoxyphenyl)methyl]piperidin-4-yl]-2-(2-hydroxyethoxy)benzamide
Also Known As: KDR-5169 free base, J1.684.796H, Benzamide, 4-amino-5-chloro-N-(1-((3-fluoro-4-methoxyphenyl)methyl)-4-piperidinyl)-2-(2-hydroxyethoxy)-, 4-amino-5-chloro-N-{1-[(3-fluoro-4-methoxyphenyl)methyl]piperidin-4-yl}-2-(2-hydroxyethoxy)benzamide, N-[1-(3-Fluoro-4-methoxybenzyl)-4-piperidinyl]-2-(2-hydroxyethoxy)-4-amino-5-chlorobenzamide
| Molecular Formula | C22H27ClFN3O4 |
|---|---|
| Molecular Weight | 451.17 g/mol |
| LogP | 2.8354 |
| Topological Polar Surface Area | 97.05 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 8 |
| Exact Mass | 451.16742 |
| Heavy Atoms | 31 |
| Complexity | 919.8693 |
Chemical Identifiers
| CAS Number | 340984-78-3 |
|---|---|
| SMILES | COC1=C(C=C(C=C1)CN2CCC(CC2)NC(=O)C3=CC(=C(C=C3OCCO)N)Cl)F |
Product Overview
KDR-5169 free base (CAS 340984-78-3), with molecular formula C22H27ClFN3O4 and molecular weight 451.17 g/mol. IUPAC: 4-amino-5-chloro-N-[1-[(3-fluoro-4-methoxyphenyl)methyl]piperidin-4-yl]-2-(2-hydroxyethoxy)benzamide.
Chemical Property Profile of KDR-5169 free base
Property Insights of KDR-5169 free base
The XLogP value of 2.8354 suggests moderate lipophilicity, balancing water solubility and membrane permeability for KDR-5169 free base. The TPSA of 97.05 Ų falls within the moderate polarity range, balancing permeability and solubility for KDR-5169 free base. Following Lipinski's Rule of Five, KDR-5169 free base has 3 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of KDR-5169 free base?
The CAS number of KDR-5169 free base is 340984-78-3.
What is the molecular formula of KDR-5169 free base?
The molecular formula of KDR-5169 free base is C22H27ClFN3O4.
What is the molecular weight of KDR-5169 free base?
The molecular weight of KDR-5169 free base is 451.17 g/mol.
Where can I buy KDR-5169 free base?
You can request a quote for KDR-5169 free base directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for KDR-5169 free base?
Yes, KEHONG BIO provides custom synthesis services for KDR-5169 free base and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.