Cloderm
TL;DR: Cloderm (CAS 34097-16-0) is a chemical compound with molecular formula C27H36ClFO5 and molecular weight 494.22 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[2-[(6S,9R,16R)-9-chloro-6-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-7,8,11,12,14,15,16,17-octahydro-6H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] 2,2-dimethylpropanoate
Also Known As: Cloderm, CLOCORTOLONE PIVALATE, Clocortolone 21-pivalate, Clocortolone pivalate [USAN], SH 863
| Molecular Formula | C27H36ClFO5 |
|---|---|
| Molecular Weight | 494.22 g/mol |
| LogP | 4.5 |
| Topological Polar Surface Area | 80.7 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 5 |
| Exact Mass | 494.22354 |
| Heavy Atoms | 34 |
| Complexity | 982.0 |
Chemical Identifiers
| CAS Number | 34097-16-0 |
|---|---|
| SMILES | C[C@@H]1CC2C3C[C@@H](C4=CC(=O)C=CC4([C@]3(C(CC2(C1C(=O)COC(=O)C(C)(C)C)C)O)Cl)C)F |
| InChIKey | SXYZQZLHAIHKKY-OROMMWLNSA-N |
Product Overview
Cloderm (CAS 34097-16-0), with molecular formula C27H36ClFO5 and molecular weight 494.22 g/mol. IUPAC: [2-[(6S,9R,16R)-9-chloro-6-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-7,8,11,12,14,15,16,17-octahydro-6H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] 2,2-dimethylpropanoate.
Chemical Property Profile of Cloderm
Property Insights of Cloderm
The XLogP value of 4.5 indicates that Cloderm is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 80.7 Ų falls within the moderate polarity range, balancing permeability and solubility for Cloderm. Following Lipinski's Rule of Five, Cloderm has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Cloderm?
The CAS number of Cloderm is 34097-16-0.
What is the molecular formula of Cloderm?
The molecular formula of Cloderm is C27H36ClFO5.
What is the molecular weight of Cloderm?
The molecular weight of Cloderm is 494.22 g/mol.
Where can I buy Cloderm?
You can request a quote for Cloderm directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Cloderm?
Yes, KEHONG BIO provides custom synthesis services for Cloderm and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.