Methotrexate-gamma-glycerophosphatidylethanolamine
TL;DR: Methotrexate-gamma-glycerophosphatidylethanolamine (CAS 34086-59-4) is a chemical compound with molecular formula C25H34N9O10P and molecular weight 651.22 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2S)-5-amino-2-[[4-[(2,4-diaminopteridin-6-yl)methyl-methylamino]benzoyl]-[2-[2,3-dihydroxypropoxy(hydroxy)phosphoryl]oxyethyl]amino]-5-oxopentanoic acid
Also Known As: Mtx-gamma-gpe, Methotrexate-gamma-glycerophosphatidylethanolamine, Methotrexate-gamma-sn-glycero-3-phosphoethanolamine, (2S)-5-amino-2-[[4-[(2,4-diaminopteridin-6-yl)methyl-methylamino]benzoyl]-[2-[2,3-dihydroxypropoxy(hydroxy)phosphoryl]oxyethyl]amino]-5-oxopentanoic acid, n2-(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)amino}benzoyl)-n2-(2-{[(2,3-dihydroxypropoxy)(hydroxy)phosphoryl]oxy}ethyl)-l-glutamine
| Molecular Formula | C25H34N9O10P |
|---|---|
| Molecular Weight | 651.22 g/mol |
| LogP | -4.9 |
| Topological Polar Surface Area | 304.0 Ų |
| Hydrogen Bond Donors | 7 |
| Hydrogen Bond Acceptors | 17 |
| Rotatable Bonds | 17 |
| Exact Mass | 651.2166 |
| Heavy Atoms | 45 |
| Complexity | 1040.0 |
Chemical Identifiers
| CAS Number | 34086-59-4 |
|---|---|
| SMILES | CN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)N(CCOP(=O)(O)OCC(CO)O)[C@@H](CCC(=O)N)C(=O)O |
| InChIKey | ZYJIOTRBRDVLST-ZVAWYAOSSA-N |
Product Overview
Methotrexate-gamma-glycerophosphatidylethanolamine (CAS 34086-59-4), with molecular formula C25H34N9O10P and molecular weight 651.22 g/mol. IUPAC: (2S)-5-amino-2-[[4-[(2,4-diaminopteridin-6-yl)methyl-methylamino]benzoyl]-[2-[2,3-dihydroxypropoxy(hydroxy)phosphoryl]oxyethyl]amino]-5-oxopentanoic acid.
Chemical Property Profile of Methotrexate-gamma-glycerophosphatidylethanolamine
Property Insights of Methotrexate-gamma-glycerophosphatidylethanolamine
The XLogP value of -4.9 indicates that Methotrexate-gamma-glycerophosphatidylethanolamine is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 304.0 Ų indicates high polarity, suggesting Methotrexate-gamma-glycerophosphatidylethanolamine may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Methotrexate-gamma-glycerophosphatidylethanolamine has 7 hydrogen bond donor(s) and 17 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Methotrexate-gamma-glycerophosphatidylethanolamine?
The CAS number of Methotrexate-gamma-glycerophosphatidylethanolamine is 34086-59-4.
What is the molecular formula of Methotrexate-gamma-glycerophosphatidylethanolamine?
The molecular formula of Methotrexate-gamma-glycerophosphatidylethanolamine is C25H34N9O10P.
What is the molecular weight of Methotrexate-gamma-glycerophosphatidylethanolamine?
The molecular weight of Methotrexate-gamma-glycerophosphatidylethanolamine is 651.22 g/mol.
Where can I buy Methotrexate-gamma-glycerophosphatidylethanolamine?
You can request a quote for Methotrexate-gamma-glycerophosphatidylethanolamine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Methotrexate-gamma-glycerophosphatidylethanolamine?
Yes, KEHONG BIO provides custom synthesis services for Methotrexate-gamma-glycerophosphatidylethanolamine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.