2-cyano-N-(4-fluorophenyl)-3-(1H-indol-3-yl)acrylamide
TL;DR: 2-cyano-N-(4-fluorophenyl)-3-(1H-indol-3-yl)acrylamide (CAS 340308-51-2) is a chemical compound with molecular formula C18H12FN3O and molecular weight 305.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-2-cyano-N-(4-fluorophenyl)-3-(1H-indol-3-yl)prop-2-enamide
Also Known As: BIM-0035841.P001, 2-cyano-N-(4-fluorophenyl)-3-(1H-indol-3-yl)acrylamide, (E)-2-cyano-N-(4-fluorophenyl)-3-(1H-indol-3-yl)acrylamide, (E)-2-cyano-N-(4-fluorophenyl)-3-(1H-indol-3-yl)prop-2-enamide
| Molecular Formula | C18H12FN3O |
|---|---|
| Molecular Weight | 305.10 g/mol |
| LogP | 3.85268 |
| Topological Polar Surface Area | 68.68 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 3 |
| Exact Mass | 305.09644 |
| Heavy Atoms | 23 |
| Complexity | 932.8051 |
Chemical Identifiers
| CAS Number | 340308-51-2 |
|---|---|
| SMILES | C1=CC=C2C(=C1)C(=CN2)/C=C(\C#N)/C(=O)NC3=CC=C(C=C3)F |
Product Overview
2-cyano-N-(4-fluorophenyl)-3-(1H-indol-3-yl)acrylamide (CAS 340308-51-2), with molecular formula C18H12FN3O and molecular weight 305.10 g/mol. IUPAC: (E)-2-cyano-N-(4-fluorophenyl)-3-(1H-indol-3-yl)prop-2-enamide.
Chemical Property Profile of 2-cyano-N-(4-fluorophenyl)-3-(1H-indol-3-yl)acrylamide
Property Insights of 2-cyano-N-(4-fluorophenyl)-3-(1H-indol-3-yl)acrylamide
The XLogP value of 3.85268 indicates that 2-cyano-N-(4-fluorophenyl)-3-(1H-indol-3-yl)acrylamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 68.68 Ų falls within the moderate polarity range, balancing permeability and solubility for 2-cyano-N-(4-fluorophenyl)-3-(1H-indol-3-yl)acrylamide. Following Lipinski's Rule of Five, 2-cyano-N-(4-fluorophenyl)-3-(1H-indol-3-yl)acrylamide has 2 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-cyano-N-(4-fluorophenyl)-3-(1H-indol-3-yl)acrylamide?
The CAS number of 2-cyano-N-(4-fluorophenyl)-3-(1H-indol-3-yl)acrylamide is 340308-51-2.
What is the molecular formula of 2-cyano-N-(4-fluorophenyl)-3-(1H-indol-3-yl)acrylamide?
The molecular formula of 2-cyano-N-(4-fluorophenyl)-3-(1H-indol-3-yl)acrylamide is C18H12FN3O.
What is the molecular weight of 2-cyano-N-(4-fluorophenyl)-3-(1H-indol-3-yl)acrylamide?
The molecular weight of 2-cyano-N-(4-fluorophenyl)-3-(1H-indol-3-yl)acrylamide is 305.10 g/mol.
Where can I buy 2-cyano-N-(4-fluorophenyl)-3-(1H-indol-3-yl)acrylamide?
You can request a quote for 2-cyano-N-(4-fluorophenyl)-3-(1H-indol-3-yl)acrylamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-cyano-N-(4-fluorophenyl)-3-(1H-indol-3-yl)acrylamide?
Yes, KEHONG BIO provides custom synthesis services for 2-cyano-N-(4-fluorophenyl)-3-(1H-indol-3-yl)acrylamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.