5-(Difluoromethyl)-3-(2-hydroxyphenyl)-4,5-dihydro-5-isoxazolol structure

5-(Difluoromethyl)-3-(2-hydroxyphenyl)-4,5-dihydro-5-isoxazolol

TL;DR: 5-(Difluoromethyl)-3-(2-hydroxyphenyl)-4,5-dihydro-5-isoxazolol (CAS 339322-22-4) is a chemical compound with molecular formula C10H9F2NO3 and molecular weight 229.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

5-(difluoromethyl)-3-(2-hydroxyphenyl)-4H-1,2-oxazol-5-ol

Also Known As: 5-(difluoromethyl)-3-(2-hydroxyphenyl)-4,5-dihydro-5-isoxazolol, 5-(difluoromethyl)-3-(2-hydroxyphenyl)-4,5-dihydroisoxazol-5-ol, 5-(difluoromethyl)-3-(2-hydroxyphenyl)-4,5-dihydro-1,2-oxazol-5-ol, (6E)-6-[5-(difluoromethyl)-5-hydroxy-1,2-oxazolidin-3-ylidene]cyclohexa-2,4-dien-1-one, (6Z)-6-[5-(difluoromethyl)-5-hydroxy-1,2-oxazolidin-3-ylidene]cyclohexa-2,4-dien-1-one

CAS: 339322-22-4
Molecular Formula C10H9F2NO3
Molecular Weight 229.06 g/mol
LogP 1.4703
Topological Polar Surface Area 62.05 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 4
Rotatable Bonds 2
Exact Mass 229.05505
Heavy Atoms 16
Complexity 435.82724

Chemical Identifiers

CAS Number 339322-22-4
SMILES C1C(=NOC1(C(F)F)O)C2=CC=CC=C2O

Product Overview

5-(Difluoromethyl)-3-(2-hydroxyphenyl)-4,5-dihydro-5-isoxazolol (CAS 339322-22-4), with molecular formula C10H9F2NO3 and molecular weight 229.06 g/mol. IUPAC: 5-(difluoromethyl)-3-(2-hydroxyphenyl)-4H-1,2-oxazol-5-ol.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 5-(Difluoromethyl)-3-(2-hydroxyphenyl)-4,5-dihydro-5-isoxazolol

XLogP
1.4703
TPSA (Topological Polar Surface Area)
62.05
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
4
Rotatable Bonds
2
Heavy Atoms
16
Complexity
435.82724
Exact Mass
229.05505
Monoisotopic Mass
229.05505
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 5-(Difluoromethyl)-3-(2-hydroxyphenyl)-4,5-dihydro-5-isoxazolol

The XLogP value of 1.4703 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 5-(Difluoromethyl)-3-(2-hydroxyphenyl)-4,5-dihydro-5-isoxazolol. The TPSA of 62.05 Ų falls within the moderate polarity range, balancing permeability and solubility for 5-(Difluoromethyl)-3-(2-hydroxyphenyl)-4,5-dihydro-5-isoxazolol. Following Lipinski's Rule of Five, 5-(Difluoromethyl)-3-(2-hydroxyphenyl)-4,5-dihydro-5-isoxazolol has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 5-(Difluoromethyl)-3-(2-hydroxyphenyl)-4,5-dihydro-5-isoxazolol?

The CAS number of 5-(Difluoromethyl)-3-(2-hydroxyphenyl)-4,5-dihydro-5-isoxazolol is 339322-22-4.

What is the molecular formula of 5-(Difluoromethyl)-3-(2-hydroxyphenyl)-4,5-dihydro-5-isoxazolol?

The molecular formula of 5-(Difluoromethyl)-3-(2-hydroxyphenyl)-4,5-dihydro-5-isoxazolol is C10H9F2NO3.

What is the molecular weight of 5-(Difluoromethyl)-3-(2-hydroxyphenyl)-4,5-dihydro-5-isoxazolol?

The molecular weight of 5-(Difluoromethyl)-3-(2-hydroxyphenyl)-4,5-dihydro-5-isoxazolol is 229.06 g/mol.

Where can I buy 5-(Difluoromethyl)-3-(2-hydroxyphenyl)-4,5-dihydro-5-isoxazolol?

You can request a quote for 5-(Difluoromethyl)-3-(2-hydroxyphenyl)-4,5-dihydro-5-isoxazolol directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 5-(Difluoromethyl)-3-(2-hydroxyphenyl)-4,5-dihydro-5-isoxazolol?

Yes, KEHONG BIO provides custom synthesis services for 5-(Difluoromethyl)-3-(2-hydroxyphenyl)-4,5-dihydro-5-isoxazolol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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