8J-919
TL;DR: 8J-919 (CAS 339102-30-6) is a chemical compound with molecular formula C25H17ClF3N3O3 and molecular weight 499.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
17-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-methylamino]-1-hydroxy-17-azapentacyclo[6.6.5.02,7.09,14.015,19]nonadeca-2,4,6,9,11,13-hexaene-16,18-dione
Also Known As: 8J-919, 17-[[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-methylamino]-1-hydroxy-17-azapentacyclo[6.6.5.02,7.09,14.015,19]nonadeca-2,4,6,9,11,13-hexaene-16,18-dione, 17-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl](methyl)amino]-1-hydroxy-17-azapentacyclo[6.6.5.0~2,7~.0~9,14~.0~15,19~]nonadeca-2,4,6,9(14),10,12-hexaene-16,18-dione, 13-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)(methyl)amino)-9-hydroxy-9,10-dihydro-9,10-[3,4]epipyrroloanthracene-12,14-dione, 17-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl](methyl)amino}-1-hydroxy-17-azapentacyclo[6.6.5.0^{2,7}.0^{9,14}.0^{15,19}]nonadeca-2,4,6,9(14),10,12-hexaene-16,18-dione
| Molecular Formula | C25H17ClF3N3O3 |
|---|---|
| Molecular Weight | 499.09 g/mol |
| LogP | 4.1012 |
| Topological Polar Surface Area | 73.74 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 2 |
| Exact Mass | 499.09106 |
| Heavy Atoms | 35 |
| Complexity | 1378.8063 |
Chemical Identifiers
| CAS Number | 339102-30-6 |
|---|---|
| SMILES | CN(C1=C(C=C(C=N1)C(F)(F)F)Cl)N2C(=O)C3C4C5=CC=CC=C5C(C3C2=O)(C6=CC=CC=C46)O |
Product Overview
8J-919 (CAS 339102-30-6), with molecular formula C25H17ClF3N3O3 and molecular weight 499.09 g/mol. IUPAC: 17-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-methylamino]-1-hydroxy-17-azapentacyclo[6.6.5.02,7.09,14.015,19]nonadeca-2,4,6,9,11,13-hexaene-16,18-dione.
Chemical Property Profile of 8J-919
Property Insights of 8J-919
The XLogP value of 4.1012 indicates that 8J-919 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 73.74 Ų falls within the moderate polarity range, balancing permeability and solubility for 8J-919. Following Lipinski's Rule of Five, 8J-919 has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 8J-919?
The CAS number of 8J-919 is 339102-30-6.
What is the molecular formula of 8J-919?
The molecular formula of 8J-919 is C25H17ClF3N3O3.
What is the molecular weight of 8J-919?
The molecular weight of 8J-919 is 499.09 g/mol.
Where can I buy 8J-919?
You can request a quote for 8J-919 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 8J-919?
Yes, KEHONG BIO provides custom synthesis services for 8J-919 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.