8L-948
TL;DR: 8L-948 (CAS 339101-84-7) is a chemical compound with molecular formula C20H18ClF3N2O4S and molecular weight 474.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[2-[(4-chlorophenyl)sulfonylmethyl]-4-(pyrrolidine-1-carbonyl)phenyl]-2,2,2-trifluoroacetamide
Also Known As: 8L-948, N-[2-{[(4-chlorophenyl)sulfonyl]methyl}-4-(1-pyrrolidinylcarbonyl)phenyl]-2,2,2-trifluoroacetamide, N-[2-[(4-chlorophenyl)sulfonylmethyl]-4-(pyrrolidine-1-carbonyl)phenyl]-2,2,2-trifluoroacetamide, N-{2-[(4-chlorobenzenesulfonyl)methyl]-4-(pyrrolidine-1-carbonyl)phenyl}-2,2,2-trifluoroacetamide
| Molecular Formula | C20H18ClF3N2O4S |
|---|---|
| Molecular Weight | 474.06 g/mol |
| LogP | 4.0507 |
| Topological Polar Surface Area | 83.55 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 5 |
| Exact Mass | 474.0628 |
| Heavy Atoms | 31 |
| Complexity | 1096.3983 |
Chemical Identifiers
| CAS Number | 339101-84-7 |
|---|---|
| SMILES | C1CCN(C1)C(=O)C2=CC(=C(C=C2)NC(=O)C(F)(F)F)CS(=O)(=O)C3=CC=C(C=C3)Cl |
Product Overview
8L-948 (CAS 339101-84-7), with molecular formula C20H18ClF3N2O4S and molecular weight 474.06 g/mol. IUPAC: N-[2-[(4-chlorophenyl)sulfonylmethyl]-4-(pyrrolidine-1-carbonyl)phenyl]-2,2,2-trifluoroacetamide.
Chemical Property Profile of 8L-948
Property Insights of 8L-948
The XLogP value of 4.0507 indicates that 8L-948 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 83.55 Ų falls within the moderate polarity range, balancing permeability and solubility for 8L-948. Following Lipinski's Rule of Five, 8L-948 has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 8L-948?
The CAS number of 8L-948 is 339101-84-7.
What is the molecular formula of 8L-948?
The molecular formula of 8L-948 is C20H18ClF3N2O4S.
What is the molecular weight of 8L-948?
The molecular weight of 8L-948 is 474.06 g/mol.
Where can I buy 8L-948?
You can request a quote for 8L-948 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 8L-948?
Yes, KEHONG BIO provides custom synthesis services for 8L-948 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.