8L-745 structure

8L-745

TL;DR: 8L-745 (CAS 339100-90-2) is a chemical compound with molecular formula C22H19Cl2N3O2 and molecular weight 427.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

ethyl 1,4-bis(4-chlorophenyl)-6-methyl-4,7-dihydropyrazolo[5,4-b]pyridine-5-carboxylate

Also Known As: 8L-745, ethyl 1,4-bis(4-chlorophenyl)-6-methyl-4,7-dihydro-1H-pyrazolo[3,4-b]pyridine-5-carboxylate, ethyl 1,4-bis(4-chlorophenyl)-6-methyl-1H,4H,7H-pyrazolo[3,4-b]pyridine-5-carboxylate, ethyl 1,4-bis(4-chlorophenyl)-6-methyl-4,7-dihydropyrazolo[3,4-b]pyridine-5-carboxylate, ethyl 1,4-bis(4-chlorophenyl)-6-methyl-2,4-dihydropyrazolo[3,4-b]pyridine-5-carboxylate

CAS: 339100-90-2
Molecular Formula C22H19Cl2N3O2
Molecular Weight 427.09 g/mol
LogP 5.5736
Topological Polar Surface Area 56.15 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 4
Rotatable Bonds 4
Exact Mass 427.08542
Heavy Atoms 29
Complexity 1086.2501

Chemical Identifiers

CAS Number 339100-90-2
SMILES CCOC(=O)C1=C(NC2=C(C1C3=CC=C(C=C3)Cl)C=NN2C4=CC=C(C=C4)Cl)C

Product Overview

8L-745 (CAS 339100-90-2), with molecular formula C22H19Cl2N3O2 and molecular weight 427.09 g/mol. IUPAC: ethyl 1,4-bis(4-chlorophenyl)-6-methyl-4,7-dihydropyrazolo[5,4-b]pyridine-5-carboxylate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of 8L-745

XLogP
5.5736
TPSA (Topological Polar Surface Area)
56.15
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
4
Rotatable Bonds
4
Heavy Atoms
29
Complexity
1086.2501
Exact Mass
427.08542
Monoisotopic Mass
427.08542
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 8L-745

The XLogP value of 5.5736 indicates that 8L-745 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 56.15 Ų, 8L-745 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 8L-745 has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 8L-745?

The CAS number of 8L-745 is 339100-90-2.

What is the molecular formula of 8L-745?

The molecular formula of 8L-745 is C22H19Cl2N3O2.

What is the molecular weight of 8L-745?

The molecular weight of 8L-745 is 427.09 g/mol.

Where can I buy 8L-745?

You can request a quote for 8L-745 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 8L-745?

Yes, KEHONG BIO provides custom synthesis services for 8L-745 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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