8J-018 structure

8J-018

TL;DR: 8J-018 (CAS 339099-47-7) is a chemical compound with molecular formula C15H9Cl4F3N2O2 and molecular weight 445.94 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

2-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-1-[5-(2,2,2-trichloroacetyl)-1H-pyrrol-3-yl]propan-1-one

Also Known As: 8J-018, 2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-1-[5-(2,2,2-trichloroacetyl)-1H-pyrrol-3-yl]propan-1-one, 2-(3-Chloro-5-(trifluoromethyl)-2-pyridinyl)-1-(5-(2,2,2-trichloroacetyl)-1H-pyrrol-3-yl)-1-propanone, 2-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-1-[5-(2,2,2-trichloroacetyl)-1H-pyrrol-3-yl]-1-propanone

CAS: 339099-47-7
Molecular Formula C15H9Cl4F3N2O2
Molecular Weight 445.94 g/mol
LogP 5.6212
Topological Polar Surface Area 62.82 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 3
Rotatable Bonds 4
Exact Mass 445.937
Heavy Atoms 26
Complexity 859.3069

Chemical Identifiers

CAS Number 339099-47-7
SMILES CC(C1=C(C=C(C=N1)C(F)(F)F)Cl)C(=O)C2=CNC(=C2)C(=O)C(Cl)(Cl)Cl

Product Overview

8J-018 (CAS 339099-47-7), with molecular formula C15H9Cl4F3N2O2 and molecular weight 445.94 g/mol. IUPAC: 2-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-1-[5-(2,2,2-trichloroacetyl)-1H-pyrrol-3-yl]propan-1-one.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of 8J-018

XLogP
5.6212
TPSA (Topological Polar Surface Area)
62.82
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
3
Rotatable Bonds
4
Heavy Atoms
26
Complexity
859.3069
Exact Mass
445.937
Monoisotopic Mass
447.93408
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 8J-018

The XLogP value of 5.6212 indicates that 8J-018 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 62.82 Ų falls within the moderate polarity range, balancing permeability and solubility for 8J-018. Following Lipinski's Rule of Five, 8J-018 has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 8J-018?

The CAS number of 8J-018 is 339099-47-7.

What is the molecular formula of 8J-018?

The molecular formula of 8J-018 is C15H9Cl4F3N2O2.

What is the molecular weight of 8J-018?

The molecular weight of 8J-018 is 445.94 g/mol.

Where can I buy 8J-018?

You can request a quote for 8J-018 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 8J-018?

Yes, KEHONG BIO provides custom synthesis services for 8J-018 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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