8H-446S
TL;DR: 8H-446S (CAS 339098-42-9) is a chemical compound with molecular formula C21H15F6NO3S and molecular weight 475.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[3,5-bis(trifluoromethyl)phenyl]-3-[(4-methoxyphenyl)methoxy]thiophene-2-carboxamide
Also Known As: 8H-446S, N-[3,5-bis(trifluoromethyl)phenyl]-3-[(4-methoxyphenyl)methoxy]thiophene-2-carboxamide, N-[3,5-bis(trifluoromethyl)phenyl]-3-[(4-methoxybenzyl)oxy]-2-thiophenecarboxamide
| Molecular Formula | C21H15F6NO3S |
|---|---|
| Molecular Weight | 475.07 g/mol |
| LogP | 6.6256 |
| Topological Polar Surface Area | 47.56 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 6 |
| Exact Mass | 475.0677 |
| Heavy Atoms | 32 |
| Complexity | 1057.8998 |
Chemical Identifiers
| CAS Number | 339098-42-9 |
|---|---|
| SMILES | COC1=CC=C(C=C1)COC2=C(SC=C2)C(=O)NC3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F |
Product Overview
8H-446S (CAS 339098-42-9), with molecular formula C21H15F6NO3S and molecular weight 475.07 g/mol. IUPAC: N-[3,5-bis(trifluoromethyl)phenyl]-3-[(4-methoxyphenyl)methoxy]thiophene-2-carboxamide.
Chemical Property Profile of 8H-446S
Property Insights of 8H-446S
The XLogP value of 6.6256 indicates that 8H-446S is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 47.56 Ų, 8H-446S exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 8H-446S has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 8H-446S?
The CAS number of 8H-446S is 339098-42-9.
What is the molecular formula of 8H-446S?
The molecular formula of 8H-446S is C21H15F6NO3S.
What is the molecular weight of 8H-446S?
The molecular weight of 8H-446S is 475.07 g/mol.
Where can I buy 8H-446S?
You can request a quote for 8H-446S directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 8H-446S?
Yes, KEHONG BIO provides custom synthesis services for 8H-446S and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.