8G-949 structure

8G-949

TL;DR: 8G-949 (CAS 339096-58-1) is a chemical compound with molecular formula C19H14F6N4O2S and molecular weight 476.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

methyl 2-amino-6-[5,7-bis(trifluoromethyl)-1,8-naphthyridin-2-yl]-5,7-dihydro-4H-thieno[2,3-c]pyridine-3-carboxylate

Also Known As: 8G-949, methyl 2-amino-6-[5,7-bis(trifluoromethyl)[1,8]naphthyridin-2-yl]-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate, methyl 2-amino-6-[5,7-bis(trifluoromethyl)-1,8-naphthyridin-2-yl]-5,7-dihydro-4H-thieno[2,3-c]pyridine-3-carboxylate, methyl 2-amino-6-[5,7-bis(trifluoromethyl)-1,8-naphthyridin-2-yl]-4H,5H,6H,7H-thieno[2,3-c]pyridine-3-carboxylate, Methyl 2-amino-6-[5,7-bis(trifluoromethyl)-1,8-naphthyridin-2-yl]-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate

CAS: 339096-58-1
Molecular Formula C19H14F6N4O2S
Molecular Weight 476.07 g/mol
LogP 4.6604
Topological Polar Surface Area 81.34 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 7
Rotatable Bonds 2
Exact Mass 476.07416
Heavy Atoms 32
Complexity 1221.219

Chemical Identifiers

CAS Number 339096-58-1
SMILES COC(=O)C1=C(SC2=C1CCN(C2)C3=NC4=C(C=C3)C(=CC(=N4)C(F)(F)F)C(F)(F)F)N

Product Overview

8G-949 (CAS 339096-58-1), with molecular formula C19H14F6N4O2S and molecular weight 476.07 g/mol. IUPAC: methyl 2-amino-6-[5,7-bis(trifluoromethyl)-1,8-naphthyridin-2-yl]-5,7-dihydro-4H-thieno[2,3-c]pyridine-3-carboxylate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of 8G-949

XLogP
4.6604
TPSA (Topological Polar Surface Area)
81.34
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
7
Rotatable Bonds
2
Heavy Atoms
32
Complexity
1221.219
Exact Mass
476.07416
Monoisotopic Mass
476.07416
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 8G-949

The XLogP value of 4.6604 indicates that 8G-949 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 81.34 Ų falls within the moderate polarity range, balancing permeability and solubility for 8G-949. Following Lipinski's Rule of Five, 8G-949 has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 8G-949?

The CAS number of 8G-949 is 339096-58-1.

What is the molecular formula of 8G-949?

The molecular formula of 8G-949 is C19H14F6N4O2S.

What is the molecular weight of 8G-949?

The molecular weight of 8G-949 is 476.07 g/mol.

Where can I buy 8G-949?

You can request a quote for 8G-949 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 8G-949?

Yes, KEHONG BIO provides custom synthesis services for 8G-949 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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