8E-392S
TL;DR: 8E-392S (CAS 339024-72-5) is a chemical compound with molecular formula C19H12Cl2F2N2O2 and molecular weight 408.02 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-chloro-1-[(4-chlorophenyl)methyl]-N-(2,4-difluorophenyl)-6-oxopyridine-3-carboxamide
Also Known As: 8E-392S, 5-chloro-1-(4-chlorobenzyl)-N-(2,4-difluorophenyl)-6-oxo-1,6-dihydro-3-pyridinecarboxamide, 5-chloro-1-[(4-chlorophenyl)methyl]-N-(2,4-difluorophenyl)-6-oxopyridine-3-carboxamide, 5-chloro-1-[(4-chlorophenyl)methyl]-N-(2,4-difluorophenyl)-6-oxo-1,6-dihydropyridine-3-carboxamide
| Molecular Formula | C19H12Cl2F2N2O2 |
|---|---|
| Molecular Weight | 408.02 g/mol |
| LogP | 4.7339 |
| Topological Polar Surface Area | 51.1 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 4 |
| Exact Mass | 408.02438 |
| Heavy Atoms | 27 |
| Complexity | 1066.295 |
Chemical Identifiers
| CAS Number | 339024-72-5 |
|---|---|
| SMILES | C1=CC(=CC=C1CN2C=C(C=C(C2=O)Cl)C(=O)NC3=C(C=C(C=C3)F)F)Cl |
Product Overview
8E-392S (CAS 339024-72-5), with molecular formula C19H12Cl2F2N2O2 and molecular weight 408.02 g/mol. IUPAC: 5-chloro-1-[(4-chlorophenyl)methyl]-N-(2,4-difluorophenyl)-6-oxopyridine-3-carboxamide.
Chemical Property Profile of 8E-392S
Property Insights of 8E-392S
The XLogP value of 4.7339 indicates that 8E-392S is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 51.1 Ų, 8E-392S exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 8E-392S has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 8E-392S?
The CAS number of 8E-392S is 339024-72-5.
What is the molecular formula of 8E-392S?
The molecular formula of 8E-392S is C19H12Cl2F2N2O2.
What is the molecular weight of 8E-392S?
The molecular weight of 8E-392S is 408.02 g/mol.
Where can I buy 8E-392S?
You can request a quote for 8E-392S directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 8E-392S?
Yes, KEHONG BIO provides custom synthesis services for 8E-392S and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.