4-Anilinoquinazoline 15
TL;DR: 4-Anilinoquinazoline 15 (CAS 338991-92-7) is a chemical compound with molecular formula C22H24ClFN4O2 and molecular weight 430.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-(4-chloro-2-fluorophenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine
Also Known As: 4-Anilinoquinazoline 15, J1.720.291J, N-(4-chloro-2-fluorophenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine, 7-(1-Methyl-4-piperidinylmethoxy)-6-methoxy-4-(2-fluoro-4-chloroanilino)quinazoline
| Molecular Formula | C22H24ClFN4O2 |
|---|---|
| Molecular Weight | 430.16 g/mol |
| LogP | 4.8951 |
| Topological Polar Surface Area | 59.51 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 6 |
| Exact Mass | 430.1572 |
| Heavy Atoms | 30 |
| Complexity | 1041.0664 |
Chemical Identifiers
| CAS Number | 338991-92-7 |
|---|---|
| SMILES | CN1CCC(CC1)COC2=C(C=C3C(=C2)N=CN=C3NC4=C(C=C(C=C4)Cl)F)OC |
Product Overview
4-Anilinoquinazoline 15 (CAS 338991-92-7), with molecular formula C22H24ClFN4O2 and molecular weight 430.16 g/mol. IUPAC: N-(4-chloro-2-fluorophenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine.
Chemical Property Profile of 4-Anilinoquinazoline 15
Property Insights of 4-Anilinoquinazoline 15
The XLogP value of 4.8951 indicates that 4-Anilinoquinazoline 15 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 59.51 Ų, 4-Anilinoquinazoline 15 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-Anilinoquinazoline 15 has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-Anilinoquinazoline 15?
The CAS number of 4-Anilinoquinazoline 15 is 338991-92-7.
What is the molecular formula of 4-Anilinoquinazoline 15?
The molecular formula of 4-Anilinoquinazoline 15 is C22H24ClFN4O2.
What is the molecular weight of 4-Anilinoquinazoline 15?
The molecular weight of 4-Anilinoquinazoline 15 is 430.16 g/mol.
Where can I buy 4-Anilinoquinazoline 15?
You can request a quote for 4-Anilinoquinazoline 15 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-Anilinoquinazoline 15?
Yes, KEHONG BIO provides custom synthesis services for 4-Anilinoquinazoline 15 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.