(3E)-3-(2-pyridylmethylene)indolin-2-one
TL;DR: (3E)-3-(2-pyridylmethylene)indolin-2-one (CAS 33899-51-3) is a chemical compound with molecular formula C14H10N2O and molecular weight 222.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(3E)-3-(pyridin-2-ylmethylidene)-1H-indol-2-one
Also Known As: (E/Z)-GSK-3beta inhibitor 1, (3E)-3-(2-pyridylmethylene)indolin-2-one, (E)-3-(Pyridin-2-ylmethylene)indolin-2-one, (3E)-3-(pyridin-2-yl-methylene)-1H-indol-2-one, (3E)-3-(pyridin-2-ylmethylidene)-1H-indol-2-one
| Molecular Formula | C14H10N2O |
|---|---|
| Molecular Weight | 222.08 g/mol |
| LogP | 2.5743 |
| Topological Polar Surface Area | 41.99 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 1 |
| Exact Mass | 222.07932 |
| Heavy Atoms | 17 |
| Complexity | 602.6291 |
Chemical Identifiers
| CAS Number | 33899-51-3 |
|---|---|
| SMILES | C1=CC=C2C(=C1)/C(=C\C3=CC=CC=N3)/C(=O)N2 |
Product Overview
(3E)-3-(2-pyridylmethylene)indolin-2-one (CAS 33899-51-3), with molecular formula C14H10N2O and molecular weight 222.08 g/mol. IUPAC: (3E)-3-(pyridin-2-ylmethylidene)-1H-indol-2-one.
Chemical Property Profile of (3E)-3-(2-pyridylmethylene)indolin-2-one
Property Insights of (3E)-3-(2-pyridylmethylene)indolin-2-one
The XLogP value of 2.5743 suggests moderate lipophilicity, balancing water solubility and membrane permeability for (3E)-3-(2-pyridylmethylene)indolin-2-one. With a topological polar surface area (TPSA) of 41.99 Ų, (3E)-3-(2-pyridylmethylene)indolin-2-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (3E)-3-(2-pyridylmethylene)indolin-2-one has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (3E)-3-(2-pyridylmethylene)indolin-2-one?
The CAS number of (3E)-3-(2-pyridylmethylene)indolin-2-one is 33899-51-3.
What is the molecular formula of (3E)-3-(2-pyridylmethylene)indolin-2-one?
The molecular formula of (3E)-3-(2-pyridylmethylene)indolin-2-one is C14H10N2O.
What is the molecular weight of (3E)-3-(2-pyridylmethylene)indolin-2-one?
The molecular weight of (3E)-3-(2-pyridylmethylene)indolin-2-one is 222.08 g/mol.
Where can I buy (3E)-3-(2-pyridylmethylene)indolin-2-one?
You can request a quote for (3E)-3-(2-pyridylmethylene)indolin-2-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (3E)-3-(2-pyridylmethylene)indolin-2-one?
Yes, KEHONG BIO provides custom synthesis services for (3E)-3-(2-pyridylmethylene)indolin-2-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.