5K-653S structure

5K-653S

TL;DR: 5K-653S (CAS 338957-87-2) is a chemical compound with molecular formula C22H13Cl2F3N2OS and molecular weight 480.01 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

2-[(2,5-dichlorophenyl)sulfanylmethyl]-3-[3-(trifluoromethyl)phenyl]quinazolin-4-one

Also Known As: 5K-653S, 2-[(2,5-dichlorophenyl)sulfanylmethyl]-3-[3-(trifluoromethyl)phenyl]quinazolin-4-one, 2-{[(2,5-dichlorophenyl)sulfanyl]methyl}-3-[3-(trifluoromethyl)phenyl]-4(3H)-quinazolinone, 2-{[(2,5-dichlorophenyl)sulfanyl]methyl}-3-[3-(trifluoromethyl)phenyl]-3,4-dihydroquinazolin-4-one

CAS: 338957-87-2
Molecular Formula C22H13Cl2F3N2OS
Molecular Weight 480.01 g/mol
LogP 7.0036
Topological Polar Surface Area 34.89 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 3
Rotatable Bonds 4
Exact Mass 480.00778
Heavy Atoms 31
Complexity 1338.6296

Chemical Identifiers

CAS Number 338957-87-2
SMILES C1=CC=C2C(=C1)C(=O)N(C(=N2)CSC3=C(C=CC(=C3)Cl)Cl)C4=CC=CC(=C4)C(F)(F)F

Product Overview

5K-653S (CAS 338957-87-2), with molecular formula C22H13Cl2F3N2OS and molecular weight 480.01 g/mol. IUPAC: 2-[(2,5-dichlorophenyl)sulfanylmethyl]-3-[3-(trifluoromethyl)phenyl]quinazolin-4-one.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 5K-653S

XLogP
7.0036
TPSA (Topological Polar Surface Area)
34.89
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
3
Rotatable Bonds
4
Heavy Atoms
31
Complexity
1338.6296
Exact Mass
480.00778
Monoisotopic Mass
480.00778
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 5K-653S

The XLogP value of 7.0036 indicates that 5K-653S is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 34.89 Ų, 5K-653S exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 5K-653S has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 5K-653S?

The CAS number of 5K-653S is 338957-87-2.

What is the molecular formula of 5K-653S?

The molecular formula of 5K-653S is C22H13Cl2F3N2OS.

What is the molecular weight of 5K-653S?

The molecular weight of 5K-653S is 480.01 g/mol.

Where can I buy 5K-653S?

You can request a quote for 5K-653S directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 5K-653S?

Yes, KEHONG BIO provides custom synthesis services for 5K-653S and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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