5K-546S structure

5K-546S

TL;DR: 5K-546S (CAS 338957-28-1) is a chemical compound with molecular formula C24H16ClF3N2OS and molecular weight 472.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

2-[2-(2-chlorophenyl)-4-phenyl-1,3-thiazol-5-yl]-N-[3-(trifluoromethyl)phenyl]acetamide

Also Known As: 5K-546S, 2-[2-(2-chlorophenyl)-4-phenyl-1,3-thiazol-5-yl]-N-[3-(trifluoromethyl)phenyl]acetamide

CAS: 338957-28-1
Molecular Formula C24H16ClF3N2OS
Molecular Weight 472.06 g/mol
LogP 7.3305
Topological Polar Surface Area 41.99 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 3
Rotatable Bonds 5
Exact Mass 472.0624
Heavy Atoms 32
Complexity 1255.5964

Chemical Identifiers

CAS Number 338957-28-1
SMILES C1=CC=C(C=C1)C2=C(SC(=N2)C3=CC=CC=C3Cl)CC(=O)NC4=CC=CC(=C4)C(F)(F)F

Product Overview

5K-546S (CAS 338957-28-1), with molecular formula C24H16ClF3N2OS and molecular weight 472.06 g/mol. IUPAC: 2-[2-(2-chlorophenyl)-4-phenyl-1,3-thiazol-5-yl]-N-[3-(trifluoromethyl)phenyl]acetamide.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of 5K-546S

XLogP
7.3305
TPSA (Topological Polar Surface Area)
41.99
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
3
Rotatable Bonds
5
Heavy Atoms
32
Complexity
1255.5964
Exact Mass
472.0624
Monoisotopic Mass
472.0624
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 5K-546S

The XLogP value of 7.3305 indicates that 5K-546S is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 41.99 Ų, 5K-546S exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 5K-546S has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 5K-546S?

The CAS number of 5K-546S is 338957-28-1.

What is the molecular formula of 5K-546S?

The molecular formula of 5K-546S is C24H16ClF3N2OS.

What is the molecular weight of 5K-546S?

The molecular weight of 5K-546S is 472.06 g/mol.

Where can I buy 5K-546S?

You can request a quote for 5K-546S directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 5K-546S?

Yes, KEHONG BIO provides custom synthesis services for 5K-546S and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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