5H-446S structure

5H-446S

TL;DR: 5H-446S (CAS 338954-13-5) is a chemical compound with molecular formula C21H23FN4O2S2 and molecular weight 446.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

N-[1-(4-ethyl-5-prop-2-enylsulfanyl-1,2,4-triazol-3-yl)-2-phenylethyl]-4-fluorobenzenesulfonamide

Also Known As: 5H-446S, N-{1-[5-(allylsulfanyl)-4-ethyl-4H-1,2,4-triazol-3-yl]-2-phenylethyl}-4-fluorobenzenesulfonamide, N-[1-(4-ethyl-5-prop-2-enylsulfanyl-1,2,4-triazol-3-yl)-2-phenylethyl]-4-fluorobenzenesulfonamide, N-{1-[4-ethyl-5-(prop-2-en-1-ylsulfanyl)-4H-1,2,4-triazol-3-yl]-2-phenylethyl}-4-fluorobenzene-1-sulfonamide, N-{1-[4-ethyl-5-(prop-2-en-1-ylsulfanyl)-1,2,4-triazol-3-yl]-2-phenylethyl}-4-fluorobenzenesulfonamide

CAS: 338954-13-5
Molecular Formula C21H23FN4O2S2
Molecular Weight 446.12 g/mol
LogP 3.9775
Topological Polar Surface Area 76.88 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 5
Rotatable Bonds 10
Exact Mass 446.12463
Heavy Atoms 30
Complexity 1083.954

Chemical Identifiers

CAS Number 338954-13-5
SMILES CCN1C(=NN=C1SCC=C)C(CC2=CC=CC=C2)NS(=O)(=O)C3=CC=C(C=C3)F

Product Overview

5H-446S (CAS 338954-13-5), with molecular formula C21H23FN4O2S2 and molecular weight 446.12 g/mol. IUPAC: N-[1-(4-ethyl-5-prop-2-enylsulfanyl-1,2,4-triazol-3-yl)-2-phenylethyl]-4-fluorobenzenesulfonamide.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of 5H-446S

XLogP
3.9775
TPSA (Topological Polar Surface Area)
76.88
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
5
Rotatable Bonds
10
Heavy Atoms
30
Complexity
1083.954
Exact Mass
446.12463
Monoisotopic Mass
446.12463
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 5H-446S

The XLogP value of 3.9775 indicates that 5H-446S is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 76.88 Ų falls within the moderate polarity range, balancing permeability and solubility for 5H-446S. Following Lipinski's Rule of Five, 5H-446S has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 5H-446S?

The CAS number of 5H-446S is 338954-13-5.

What is the molecular formula of 5H-446S?

The molecular formula of 5H-446S is C21H23FN4O2S2.

What is the molecular weight of 5H-446S?

The molecular weight of 5H-446S is 446.12 g/mol.

Where can I buy 5H-446S?

You can request a quote for 5H-446S directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 5H-446S?

Yes, KEHONG BIO provides custom synthesis services for 5H-446S and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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