![2-{4-[5-(2,4-dichlorophenyl)-2-furyl]-1,3-thiazol-2-yl}-3-(dimethylamino)acrylonitrile structure](/static/products/3387/338786-21-3.webp)
2-{4-[5-(2,4-dichlorophenyl)-2-furyl]-1,3-thiazol-2-yl}-3-(dimethylamino)acrylonitrile
TL;DR: 2-{4-[5-(2,4-dichlorophenyl)-2-furyl]-1,3-thiazol-2-yl}-3-(dimethylamino)acrylonitrile (CAS 338786-21-3) is a chemical compound with molecular formula C18H13Cl2N3OS and molecular weight 389.02 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[4-[5-(2,4-dichlorophenyl)furan-2-yl]-1,3-thiazol-2-yl]-3-(dimethylamino)prop-2-enenitrile
Also Known As: 2-{4-[5-(2,4-dichlorophenyl)-2-furyl]-1,3-thiazol-2-yl}-3-(dimethylamino)acrylonitrile, 2-[4-[5-(2,4-dichlorophenyl)-2-furyl]-1,3-thiazol-2-yl]-3-dimethylamino-prop-2-enenitrile, 2-[4-[5-(2,4-dichlorophenyl)furan-2-yl]-1,3-thiazol-2-yl]-3-(dimethylamino)prop-2-enenitrile
| Molecular Formula | C18H13Cl2N3OS |
|---|---|
| Molecular Weight | 389.02 g/mol |
| LogP | 5.80298 |
| Topological Polar Surface Area | 53.06 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 4 |
| Exact Mass | 389.01562 |
| Heavy Atoms | 25 |
| Complexity | 982.3703 |
Chemical Identifiers
| CAS Number | 338786-21-3 |
|---|---|
| SMILES | CN(C)C=C(C#N)C1=NC(=CS1)C2=CC=C(O2)C3=C(C=C(C=C3)Cl)Cl |
Product Overview
2-{4-[5-(2,4-dichlorophenyl)-2-furyl]-1,3-thiazol-2-yl}-3-(dimethylamino)acrylonitrile (CAS 338786-21-3), with molecular formula C18H13Cl2N3OS and molecular weight 389.02 g/mol. IUPAC: 2-[4-[5-(2,4-dichlorophenyl)furan-2-yl]-1,3-thiazol-2-yl]-3-(dimethylamino)prop-2-enenitrile.
Chemical Property Profile of 2-{4-[5-(2,4-dichlorophenyl)-2-furyl]-1,3-thiazol-2-yl}-3-(dimethylamino)acrylonitrile
Property Insights of 2-{4-[5-(2,4-dichlorophenyl)-2-furyl]-1,3-thiazol-2-yl}-3-(dimethylamino)acrylonitrile
The XLogP value of 5.80298 indicates that 2-{4-[5-(2,4-dichlorophenyl)-2-furyl]-1,3-thiazol-2-yl}-3-(dimethylamino)acrylonitrile is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 53.06 Ų, 2-{4-[5-(2,4-dichlorophenyl)-2-furyl]-1,3-thiazol-2-yl}-3-(dimethylamino)acrylonitrile exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-{4-[5-(2,4-dichlorophenyl)-2-furyl]-1,3-thiazol-2-yl}-3-(dimethylamino)acrylonitrile has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-{4-[5-(2,4-dichlorophenyl)-2-furyl]-1,3-thiazol-2-yl}-3-(dimethylamino)acrylonitrile?
The CAS number of 2-{4-[5-(2,4-dichlorophenyl)-2-furyl]-1,3-thiazol-2-yl}-3-(dimethylamino)acrylonitrile is 338786-21-3.
What is the molecular formula of 2-{4-[5-(2,4-dichlorophenyl)-2-furyl]-1,3-thiazol-2-yl}-3-(dimethylamino)acrylonitrile?
The molecular formula of 2-{4-[5-(2,4-dichlorophenyl)-2-furyl]-1,3-thiazol-2-yl}-3-(dimethylamino)acrylonitrile is C18H13Cl2N3OS.
What is the molecular weight of 2-{4-[5-(2,4-dichlorophenyl)-2-furyl]-1,3-thiazol-2-yl}-3-(dimethylamino)acrylonitrile?
The molecular weight of 2-{4-[5-(2,4-dichlorophenyl)-2-furyl]-1,3-thiazol-2-yl}-3-(dimethylamino)acrylonitrile is 389.02 g/mol.
Where can I buy 2-{4-[5-(2,4-dichlorophenyl)-2-furyl]-1,3-thiazol-2-yl}-3-(dimethylamino)acrylonitrile?
You can request a quote for 2-{4-[5-(2,4-dichlorophenyl)-2-furyl]-1,3-thiazol-2-yl}-3-(dimethylamino)acrylonitrile directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-{4-[5-(2,4-dichlorophenyl)-2-furyl]-1,3-thiazol-2-yl}-3-(dimethylamino)acrylonitrile?
Yes, KEHONG BIO provides custom synthesis services for 2-{4-[5-(2,4-dichlorophenyl)-2-furyl]-1,3-thiazol-2-yl}-3-(dimethylamino)acrylonitrile and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.