2L-011
TL;DR: 2L-011 (CAS 338775-12-5) is a chemical compound with molecular formula C18H12ClF3N6OS and molecular weight 452.04 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]sulfanyl]-6-(4-methoxyphenyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine
Also Known As: 2L-011, 2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfanyl-6-(4-methoxyphenyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine, 2-((3-Chloro-5-(trifluoromethyl)-2-pyridinyl)sulfanyl)-6-(4-methoxyphenyl)(1,2,4)triazolo[1,5-a]pyrimidin-7-amine, 2-{[3-chloro-5-(trifluoromethyl)-2-pyridinyl]sulfanyl}-6-(4-methoxyphenyl)[1,2,4]triazolo[1,5-a]pyrimidin-7-amine, 2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfanyl}-6-(4-methoxyphenyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine
| Molecular Formula | C18H12ClF3N6OS |
|---|---|
| Molecular Weight | 452.04 g/mol |
| LogP | 4.6005 |
| Topological Polar Surface Area | 91.22 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 4 |
| Exact Mass | 452.0434 |
| Heavy Atoms | 30 |
| Complexity | 1229.2946 |
Chemical Identifiers
| CAS Number | 338775-12-5 |
|---|---|
| SMILES | COC1=CC=C(C=C1)C2=C(N3C(=NC(=N3)SC4=C(C=C(C=N4)C(F)(F)F)Cl)N=C2)N |
Product Overview
2L-011 (CAS 338775-12-5), with molecular formula C18H12ClF3N6OS and molecular weight 452.04 g/mol. IUPAC: 2-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]sulfanyl]-6-(4-methoxyphenyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine.
Chemical Property Profile of 2L-011
Property Insights of 2L-011
The XLogP value of 4.6005 indicates that 2L-011 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 91.22 Ų falls within the moderate polarity range, balancing permeability and solubility for 2L-011. Following Lipinski's Rule of Five, 2L-011 has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2L-011?
The CAS number of 2L-011 is 338775-12-5.
What is the molecular formula of 2L-011?
The molecular formula of 2L-011 is C18H12ClF3N6OS.
What is the molecular weight of 2L-011?
The molecular weight of 2L-011 is 452.04 g/mol.
Where can I buy 2L-011?
You can request a quote for 2L-011 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2L-011?
Yes, KEHONG BIO provides custom synthesis services for 2L-011 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.