2K-919 structure

2K-919

TL;DR: 2K-919 (CAS 338775-03-4) is a chemical compound with molecular formula C18H10Cl3F3N4O3 and molecular weight 491.98 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

5-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-methylamino]-3-(2,6-dichlorophenyl)-3a,6a-dihydropyrrolo[3,4-d][1,2]oxazole-4,6-dione

Also Known As: 2K-919, 5-((3-Chloro-5-(trifluoromethyl)-2-pyridinyl)(methyl)amino)-3-(2,6-dichlorophenyl)-3ah-pyrrolo[3,4-d]isoxazole-4,6(5H,6aH)-dione, 5-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-methylamino]-3-(2,6-dichlorophenyl)-3a,6a-dihydropyrrolo[3,4-d][1,2]oxazole-4,6-dione, 5-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl](methyl)amino}-3-(2,6-dichlorophenyl)-3aH,4H,5H,6H,6aH-pyrrolo[3,4-d][1,2]oxazole-4,6-dione, 5-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl](methyl)amino]-3-(2,6-dichlorophenyl)-3aH-pyrrolo[3,4-d]isoxazole-4,6(5H,6aH)-dione

CAS: 338775-03-4
Molecular Formula C18H10Cl3F3N4O3
Molecular Weight 491.98 g/mol
LogP 4.1999
Topological Polar Surface Area 75.1 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 6
Rotatable Bonds 3
Exact Mass 491.97705
Heavy Atoms 31
Complexity 1121.5135

Chemical Identifiers

CAS Number 338775-03-4
SMILES CN(C1=C(C=C(C=N1)C(F)(F)F)Cl)N2C(=O)C3C(C2=O)ON=C3C4=C(C=CC=C4Cl)Cl

Product Overview

2K-919 (CAS 338775-03-4), with molecular formula C18H10Cl3F3N4O3 and molecular weight 491.98 g/mol. IUPAC: 5-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-methylamino]-3-(2,6-dichlorophenyl)-3a,6a-dihydropyrrolo[3,4-d][1,2]oxazole-4,6-dione.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 2K-919

XLogP
4.1999
TPSA (Topological Polar Surface Area)
75.1
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
6
Rotatable Bonds
3
Heavy Atoms
31
Complexity
1121.5135
Exact Mass
491.97705
Monoisotopic Mass
491.97705
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 2K-919

The XLogP value of 4.1999 indicates that 2K-919 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 75.1 Ų falls within the moderate polarity range, balancing permeability and solubility for 2K-919. Following Lipinski's Rule of Five, 2K-919 has 0 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 2K-919?

The CAS number of 2K-919 is 338775-03-4.

What is the molecular formula of 2K-919?

The molecular formula of 2K-919 is C18H10Cl3F3N4O3.

What is the molecular weight of 2K-919?

The molecular weight of 2K-919 is 491.98 g/mol.

Where can I buy 2K-919?

You can request a quote for 2K-919 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 2K-919?

Yes, KEHONG BIO provides custom synthesis services for 2K-919 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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